| Description : |
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6. Several transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
104.1 kDa |
| AA Sequence : |
MALAVLRVLEPFPTETPPLAVLLPP GGPWPAAELGLVLALRPAGESPAGP ALLVAALEGPDAGTEEQGPGPPQLL VSRALLRLLALGSGAWVRARAVRRP PALGWALLGTSLGPGLGPRVGPLLV RRGETLPVPGPRVLETRPALQGLLG PGTRLAVTELRGRARLCPESGDSSR PPPPPVVSSFAVSGTVRRLQGVLGG TGDSLGVSRSCLRGLGLFQGEWVWV AQARESSNTSQPHLARVQVLEPRWD LSDRLGPGSGPLGEPLADGLALVPA TLAFNLGCDPLEMGELRIQRYLEGS IAPEDKGSCSLLPGPPFARELHIEI VSSPHYSTNGNYDGVLYRHFQIPRV VQEGDVLCVPTIGQVEILEGSPEKL PRWREMFFKVKKTVGEAPDGPASAY LADTTHTSLYMVGSTLSPVPWLPSE ESTLWSSLSPPGLEALVSELCAVLK PRLQPGGALLTGTSSVLLRGPPGCG KTTVVAAACSHLGLHLLKVPCSSLC AESSGAVETKLQAIFSRARRCRPAV LLLTAVDLLGRDRDGLGEDARVMAV LRHLLLNEDPLNSCPPLMVVATTSR AQDLPADVQTAFPHELEVPALSEGQ RLSILRALTAHLPLGQEVNLAQLAR RCAGFVVGDLYALLTHSSRAACTRI KNSGLAGGLTEEDEGELCAAGFPLL AEDFGQALEQLQTAHSQAVGAPKIP SVSWHDVGGLQEVKKEILETIQLPL EHPELLSLGLRRSGLLLHGPPGTGK TLLAKAVATECSLTFLSVKGPELIN MYVGQSEENVREVFARARAAAPCII FFDELDSLAPSRGRSGDSGGVMDRV VSQLLAELDGLHSTQDVFVIGATNR PDLLDPALLRPGRFDKLVFVGANED RASQLRVLSAITRKFKLEPSVSLVN VLDCCPPQLTGADLYSLCSDAMTAA LKRRVHDLEEGLEPGSSALMLTMED LLQAAARLQPSVSEQELLRYKRIQR KFAACTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
