Recombinant Human PGBD3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PGBD3-1367H
• Product Overview: PGBD3 MS Standard C13 and N15-labeled recombinant protein (NP_736609) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is a member of a small family of genes derived from piggyBac transposable elements. The encoded protein contains a zinc-ribbon domain characteristic of transposon-derived proteins and may function as a regulator of transcription. Alternative splicing occurs between a splice site from exon 5 of the adjacent upstream gene 'excision repair cross-complementation group 6' (ERCC6, GeneID: 2074) and the 3' splice site upstream of the open reading frame (ORF) of this gene, which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene. Pseudogenes for this gene are defined on chromosomes 4, 5 and 12.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 67.6 kDa
• AA Sequence: MPRTLSLHEITDLLETDDSIEASAI VIQPPENATAPVSDEESGDEEGGTI NNLPGSLLHTAAYLIQDGSDAESDS DDPSYAPKDDSPDEVPSTFTVQQPP PSRRRKMTKILCKWKKADLTVQPVA GRVTAPPNDFFTVMRTPTEILELFL DDEVIELIVKYSNLYACSKGVHLGL TSSEFKCFLGIIFLSGYVSVPRRRM FWEQRTDVHNVLVSAAMRRDRFETI FSNLHVADNANLDPVDKFSKLRPLI SKLNERCMKFVPNETYFSFDEFMVP YFGRHGCKQFIRGKPIRFGYKFWCG ATCLGYICWFQPYQGKNPNTKHEEY GVGASLVLQFSEALTEAHPGQYHFV FNNFFTSIALLDKLSSMGHQATGTV RKDHIDKVPLESDVALKKKERGTFD YRIDGKGNIVCRWNDNSVVTVASSG AGIHPLCLVSRYSQKLKKKIQVQQP NMIKVYNQFMGGVDRADENIDKYRA SIRGKKWYSSPLLFCFELVLQNAWQ LHKTYDEKPVDFLEFRRRVVCHYLE THGHPPEPGQKGRPQKRNIDSRYDG INHVIVKQGKQTRCAECHKNTTFRC EKCDVALHVKCSVEYHTETRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PGBD3 piggyBac transposable element derived 3 [ Homo sapiens (human) ]
• Official Symbol: PGBD3
• Synonyms: PGBD3; piggyBac transposable element derived 3; piggyBac transposable element-derived protein 3; FLJ90201
• Gene ID: 267004
• mRNA Refseq: NM_170753
• Protein Refseq: NP_736609
• UniProt ID: Q8N328