Recombinant Human Phosphatase, Orphan 2, His-tagged
Cat.No. : | PHOSPHO2-1574H |
Product Overview : | Recombinant human PHOSPHO2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
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Cat. No. : | PHOSPHO2-1574H |
Description : | Pyridoxal phosphate phosphatase PHOSPHO2, orphan 2, also known as PHOSPHO2, belongs to the haloaciddehalogenase(HAD) superfamily. Phosphatase has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). PHOSPHO 1, a phosphoethanolamine/phosphocholine phosphatase, is upregulated in mineralising cells and is thought to be involved in the generation of inorganic phosphate for bone mineralization. PHOSPHO2 is a putative phosphatase sharing 42% sequence identity with PHOSPHO1. PHOSPHO1 and PHOSPHO2 are very similar, but surprisingly, recombinant PHOSPHO2 hydrolyses phosphoethanolamine and phosphocholine relatively poorly. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing1mM DTT, 10% glycerol, 0.1M NaCl. |
Molecular Weight : | 30.3 kDa (265aa), confirmed by MALDI-TOF. |
Purity : | >85% by SDS-PAGE |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MGSHMKILLV FDFDNTIIDD NSDTWIVQCA PNKKLPIELR DSYRKGFWTE FMGRVFKYLG DKGVREHEMKRAVTSLPFTP GMVELFNFIR KNKDKFDCII ISDSNSVFID WVLEAASFHD IFDKVFTNPA AFNSNGHLTV ENYHTHSCNR CPKNLCKKVV LIEFVDKQLQ QGVNYTQIVY IGDGGNDVCP VTFLKNDDVA MPRKGYTLQK TLSRMSQNLE PMEYSVVVWS SGVDIISHLQ FLIKD |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Metabolic pathways; Vitamin B6 metabolism |
Gene Name : | PHOSPHO2 phosphatase, orphan 2 [ Homo sapiens ] |
Official Symbol : | PHOSPHO2 |
Synonyms : | PHOSPHO2; phosphatase, orphan 2; MGC22679; MGC111048; pyridoxal phosphate phosphatase PHOSPHO2; OTTHUMP00000204769; OTTHUMP00000204770; OTTHUMP00000204771; OTTHUMP00000204772; EC 3.1.3.74; MGC111048 |
Gene ID : | 493911 |
mRNA Refseq : | NM_001008489 |
Protein Refseq : | NP_001008489 |
UniProt ID : | Q8TCD6 |
Chromosome Location : | 2q31.1 |
Function : | hydrolase activity; metal ion binding; pyridoxal phosphatase activity |
Products Types
◆ Recombinant Protein | ||
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PHOSPHO2-12750M | Recombinant Mouse PHOSPHO2 Protein | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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