Recombinant Human Phosphomannomutase 2, His-tagged
Cat.No. : | PMM2-2822H |
Product Overview : | Recombinant humanPMM2 protein,fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 30.2 kDa (266aa), confirmed by MALDI-TOF. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PMM2-2822H |
Description : | PMM2, also known asPhosphomannomutase 2, belongs to the eukaryotic PMM family. PMM2 is involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. It catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mutations in PMM2 are associated with Congenital disorders of glycosylation (CDG)-Ia, an autosomal recessive disorder characterized by central nervous system dysfunction and multiorgan failure. |
Source : | E.coli. |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MAAPGPALCL FDVDGTLTAP RQKITKEMDD FLQKLRQKIK IGVVGGSDFE KVQEQLGNDV VEKYDYVFPE NGLVAYKDGK LLCRQNIQSH LGEALIQDLI NYCLSYIAKI KLPKKRGTFI EFRNGMLNVS PIGRSCSQEE RIEFYELDKK ENIRQKFVAD LRKEFAGKGL TFSIGGQISF DVFPDGWDKR YCLRHVENDG YKTIYFFGDK TMPGGNDHEI FTDPRTMGYS VTAPEDTRRI CELLFS |
Purity : | > 95% by SDS – PAGE. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT, 0.1M NaCl. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | PMM2 phosphomannomutase 2 [ Homo sapiens ] |
Synonyms : | PMM2; phosphomannomutase 2; CDG1; CDGS; CDG1a; PMM 2; EC 5.4.2.8; CDG1A |
Gene ID : | 5373 |
mRNA Refseq : | NM_000303 |
Protein Refseq : | NP_000294 |
MIM : | 601785 |
UniProt ID : | O15305 |
Chromosome Location : | 16p13 |
Pathway : | Amino sugar and nucleotide sugar metabolism; Fructose and mannose metabolism; Metabolic pathways |
Function : | isomerase activity; phosphomannomutase activity |
Products Types
◆ Recombinant Protein | ||
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Pmm2-4956M | Recombinant Mouse Pmm2 Protein, Myc/DDK-tagged | +Inquiry |
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PMM2-3115C | Recombinant Chicken PMM2 | +Inquiry |
◆ Lysates | ||
PMM2-3087HCL | Recombinant Human PMM2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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