Recombinant Human PIGR protein, His-tagged

• Cat.No.: PIGR-1470H
• Product Overview: Recombinant Human PIGR aa. (Pro462~Ala561 (Accession # P01833)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 13 kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Pro462~Ala561 (Accession # P01833)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method).
• Purity: >95%,
• Characteristic: The isoelectric point is 6.7.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: PIGR polymeric immunoglobulin receptor [ Homo sapiens (human) ]
• Official Symbol: PIGR
• Synonyms: hepatocellular carcinoma associated protein TB6; poly-Ig receptor; polymeric immunoglobulin receptor
• Gene ID: 5284
• mRNA Refseq: NM_002644.3
• Protein Refseq: NP_002635.2
• UniProt ID: P01833