Recombinant Human PIM3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PIM3-3656H
• Product Overview: PIM3 MS Standard C13 and N15-labeled recombinant protein (NP_001001852) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 35.7 kDa
• AA Sequence: MLLSKFGSLAHLCGPGGVDHLPVKI LQPAKADKESFEKAYQVGAVLGSGG FGTVYAGSRIADGLPVAVKHVVKER VTEWGSLGGATVPLEVVLLRKVGAA GGARGVIRLLDWFERPDGFLLVLER PEPAQDLFDFITERGALDEPLARRF FAQVLAAVRHCHSCGVVHRDIKDEN LLVDLRSGELKLIDFGSGALLKDTV YTDFDGTRVYSPPEWIRYHRYHGRS ATVWSLGVLLYDMVCGDIPFEQDEE ILRGRLLFRRRVSPECQQLIRWCLS LRPSERPSLDQIAAHPWMLGADGGA PESCDLRLCTLDPDDVASTTSSSES LTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PIM3 pim-3 oncogene [ Homo sapiens (human) ]
• Official Symbol: PIM3
• Synonyms: PIM3; pim-3 oncogene; serine/threonine-protein kinase pim-3; serine/threonine kinase Pim-3; pim-3
• Gene ID: 415116
• mRNA Refseq: NM_001001852
• Protein Refseq: NP_001001852
• MIM: 610580
• UniProt ID: Q86V86