| Description : |
This gene encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
106.6 kDa |
| AA Sequence : |
MAKAGRAGGPPPGGGAPWHLRNVLS DSVESSDDEFFDAREEMAEGKNAIL IGMSQWNSNDLVEQIETMGKLDEHQ GEGTAPCTSSILQEKQRELYRVSLR RQRFPAQGSIEIHEDSEEGCPQRSC KTHVLLLVLHGGNILDTGAGDPSCK AADIHTFSSVLEKVTRAHFPAALGH ILIKFVPCPAICSEAFSLVSHLNPY SHDEGCLSSSQDHVPLAALPLLAIS SPQYQDAVATVIERANQVYREFLKS SDGIGFSGQVCLIGDCVGGLLAFDA ICYSAGPSGDSPASSSRKGSISSTQ DTPVAVEEDCSLASSKRLSKSNIDI SSGLEDEEPKRPLPRKQSDSSTYDC EAITQHHAFLSSIHSSVLKDESETP AAGGPQLPEVSLGRFDFDVSDFFLF GSPLGLVLAMRRTVLPGLDGFQVRP ACSQVYSFFHCADPSASRLEPLLEP KFHLVPPVSVPRYQRFPLGDGQSLL LADALHTHSPLFLEGSSRDSPPLLD APASPPQASRFQRPGRRMSEGSSHS ESSESSDSMAPVGASRITAKWWGSK RIDYALYCPDVLTAFPTVALPHLFH ASYWESTDVVAFILRQVMRYESVNI KESARLDPAALSPANPREKWLRKRT QVKLRNVTANHRANDVIAAEDGPQV LVGRFMYGPLDMVALTGEKVDILVM AEPSSGRWVHLDTEITNSSGRITYN VPRPRRLGVGVYPVKMVVRGDQTCA MSYLTVLPRGMECVVFSIDGSFAAS VSIMGSDPKVRPGAVDVVRHWQDLG YMILYITGRPDMQKQRVVSWLSQHN FPQGMIFFSDGLVHDPLRQKAIFLR NLMQECFIKISAAYGSTKDISVYSV LGLPASQIFIVGRPTKKYQTQCQFL SEGYAAHLAALEASHRSRPKKNNSR MILRKGSFGLHAQPEFLRKRNHLRR TMSVQQPDPPAANPKPERAQSQPES DKDHERPLPALSWARGPPKFESVPT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
