Recombinant Human PITX2 Protein, GST-HIS-tagged
Cat.No. : | PITX2-134H |
Product Overview : | Recombinant Human PITX2, transcript variant 3, fused with N-terminall GST and C-terminall His was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
Source : | E. coli |
Species : | Human |
Tag : | GST-HIS |
Form : | 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl. |
Molecular Mass : | 61.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | PITX2 paired-like homeodomain 2 [ Homo sapiens ] |
Official Symbol : | PITX2 |
Synonyms : | PITX2; paired-like homeodomain 2; IHG2, IRID2, paired like homeodomain transcription factor 2 , RGS, RIEG, RIEG1; pituitary homeobox 2; ARP1; Brx1; IGDS; Otlx2; RS; solurshin; all1-responsive gene 1; homeobox protein PITX2; ALL1-responsive protein ARP1; paired-like homeodomain transcription factor 2; rieg bicoid-related homeobox transcription factor 1; RGS; IDG2; IHG2; PTX2; RIEG; IGDS2; IRID2; RIEG1; MGC20144; MGC111022; |
Gene ID : | 5308 |
mRNA Refseq : | NM_000325 |
Protein Refseq : | NP_000316 |
MIM : | 601542 |
UniProt ID : | Q99697 |
Products Types
◆ Recombinant Protein | ||
PITX2-6770M | Recombinant Mouse PITX2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PITX2-4137R | Recombinant Rat PITX2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PITX2-135H | Recombinant Human PITX2 Protein, HIS-tagged | +Inquiry |
PITX2-6568C | Recombinant Chicken PITX2 | +Inquiry |
PITX2-4477R | Recombinant Rat PITX2 Protein | +Inquiry |
◆ Lysates | ||
PITX2-3164HCL | Recombinant Human PITX2 293 Cell Lysate | +Inquiry |
PITX2-3163HCL | Recombinant Human PITX2 293 Cell Lysate | +Inquiry |
PITX2-3165HCL | Recombinant Human PITX2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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