Recombinant Human PLA2G1B, His-tagged
Cat.No. : | PLA2G1B-898H |
Product Overview : | Recombinant Human PLA2G1B protein (Met 1 - Ser 148), fused with a his tag at the C-terminus, was expressed inHuman Cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PLA2G1B-898H |
Description : | Phospholipase A2, also known as Phosphatidylcholine 2-acylhydrolase 1B, Group IB phospholipase A2, PLA2 and PLA2G1B, is a secreted protein which belongs to the phospholipase A2 family. Phospholipase A2 / PLA2G1B catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic Phospholipase A2 / PLA2G1B enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. |
Source : | Human Cells. |
Molecular Mass : | The recombinant human PLA2G1B comprises 144 amino acids after removal of the signal peptide, and has a predicted molecular mass of 16.2 kDa. rh PLA2G1B migrates as an approximately 19 kDa band in SDS-PAGE under reducing conditions. |
Predicted N Terminal : | Asp 16. |
Purity : | > 92 % as determined by SDS-PAGE. |
Formulation : | Lyophilized from sterile 10mM Tris, 5mM CaCl, pH 8.0. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Reconstitution : | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70℃. |
Storage : | Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | PLA2G1B phospholipase A2, group IB (pancreas) [ Homo sapiens ] |
Synonyms : | PLA2G1B; PLA2G1B phospholipase A2, group IB (pancreas); PLA2; PLA2A; PPLA2; MGC119834; MGC119835; phospholipase A2 group IB; phosphatidylcholine 2-acylhydrolase |
Gene ID : | 5319 |
mRNA Refseq : | NM_000928 |
Protein Refseq : | NP_000919 |
MIM : | 172410 |
UniProt ID : | P04054 |
Chromosome Location : | 12q23-q24.1 |
Pathway : | Arachidonic acid metabolism; Ether lipid metabolism; Fc epsilon RI signaling pathway; Linoleic acid metabolism; Long-term depression; MAPK signaling pathway; Metabolic pathways; VEGF signaling pathway; Vascular smooth muscle contraction; alpha-Linolenic acid metabolism; Glycerophospholipid metabolism; GnRH signaling pathway |
Function : | bile acid binding; calcium ion binding; calcium-dependent phospholipase A2 activity; cell surface binding; hydrolase activity; receptor binding |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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