| Description : |
Plexins are a family of large, transmembrane receptors for multiple classes of semaphorins in vertebrates. Plexins are widely expressed, and regions of their extracellular domain are homologus to both scatter factor receptors and semaphorin domains. Plexins may act as semaphorin receptors alone or in combination with neuropilins. Plexins are divided into four subfamilies designated plexin-A, -B, -C, and -D. Drosophila plexin-A is a receptor for class I semaphorins and controls motor and axon guidance. Plexin-A3 mediates cellrepelling cues. Plexins B and C are receptors for Sema 4 and Sema 7, respectively. |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
His |
| Molecular Mass : |
~110 kDa |
| AA Sequence : |
MADEPVWRSEQAIGAIAASQEDGVF VASGSCLDQLDYSLEHSLSRLYRDQ AGNCTEPVSLAPPARPRPGSSFSKL LLPYREGAAGLGGLLLTGWTFDRGA CEVRPLGNLSRNSLRNGTEVVSCHP QGSTAGVVYRAGRNNRWYLAVAATY VLPEPETASRCNPAASDHDTAIALK DTEGRSLATQELGRLKLCEGAGSLH FVDAFLWNGSIYFPYYPYNYTSGAA TGWPSMARIAQSTEVLFQGQASLDC GHGHPDGRRLLLSSSLVEALDVWAG VFSAAAGEGQERRSPTTTALCLFRM SEIQARAKRVSWDFKTAESHCKEGD QPERVQPIASSTLIHSDLTSVYGTV VMNRTVLFLGTGDGQLLKVILGENL TSNCPEVIYEIKEETPVFYKLVPDP VKNIYIYLTAGKEVRRIRVANCNKH KSCSECLTATDPHCGWCHSLQRCTF QGDCVHSENLENWLDISSGAKKCPK IQIIRSSKEKTTVTMVGSFSPRHSK CMVKNVDSSRELCQNKSQPNRTCTC SIPTRATYKDVSVVNVMFSFGSWNL SDRFNFTNCSSLKECPACVETGCAW CKSARRCIHPFTACDPSDYERNQEQ CPVAVEKTSGGGRPKENKGNRTNQA LQVFYIKSIEPQKVSTLGKSNVIVT GANFTRASNITMILKGTSTCDKDVI QVSHVLNDTHMKFSLPSSRKEMKDV CIQFDGGNCSSVGSLSYIALPHCSL IFPATTWISGGQNITMMGRNFDVID NLIISHELKGNINVSEYCVATYCGF LAPSLKSSKVRTNVTVKLRVQDTYL DCGTLQYREDPRFTGYRVESEVDTE LEVKIQKENDNFNISKKDIEITLFH GENGQLNCSFENITRNQDLTTILCK IKGIKTASTIANSSKKVRVKLGNLE LYVEQESVPST |
| Purity : |
Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
| Notes : |
For research use only, not for use in diagnostic procedure. |
| Storage : |
Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
| Storage Buffer : |
PBS, 4M Urea, pH7.4 |
