Recombinant Human PMP22 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PMP22-4473H
• Product Overview: PMP22 MS Standard C13 and N15-labeled recombinant protein (NP_696997) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 17.7 kDa
• AA Sequence: MLLLLLSIIVLHVAVLVLLFVSTIV SQWIVGNGHATDLWQNCSTSSSGNV HHCFSSSPNEWLQSVQATMILSIIF SILSLFLFFCQLFTLTKGGRFYITG IFQILAGLCVMSAAAIYTVRHPEWH LNSDYSYGFAYILAWVAFPLALLSG VIYVILRKRETRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PMP22 peripheral myelin protein 22 [ Homo sapiens (human) ]
• Official Symbol: PMP22
• Synonyms: PMP22; peripheral myelin protein 22; GAS 3; HNPP; Sp110; PMP-22; growth arrest-specific 3; growth arrest-specific protein 3; DSS; CMT1A; CMT1E; GAS-3; HMSNIA; MGC20769
• Gene ID: 5376
• mRNA Refseq: NM_153322
• Protein Refseq: NP_696997
• MIM: 601097
• UniProt ID: Q01453