Recombinant Human PMPCA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PMPCA-1676H
• Product Overview: PMPCA MS Standard C13 and N15-labeled recombinant protein (NP_055975) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 58.1 kDa
• AA Sequence: MAAVVLAATRLLRGSGSWGCSRLRF GPPAYRRFSSGGAYPNIPLSSPLPG VPKPVFATVDGQEKFETKVTTLDNG LRVASQNKFGQFCTVGILINSGSRY EAKYLSGIAHFLEKLAFSSTARFDS KDEILLTLEKHGGICYCQTSRDTTM YAVSADSKGLDTVVALLADVVLQPR LTDEEVEMTRMAVQFELEDLNLRPD PEPLLTEMIHEAAYRENTVGLHRFC PTENVAKINREVLHSYLRNYYTPDR MVLAGVGVEHEHLVDCARKYLLGVQ PAWGSAEAVDIDRSVAQYTGGIAKL ERDMSNVSLGPTPIPELTHIMVGLE SCSFLEEDFIPFAVLNMMMGGGGSF SAGGPGKGMFSRLYLNVLNRHHWMY NATSYHHSYEDTGLLCIHASADPRQ VREMVEIITKEFILMGGTVDTVELE RAKTQLTSMLMMNLESRPVIFEDVG RQVLATRSRKLPHELCTLIRNVKPE DVKRVASKMLRGKPAVAALGDLTDL PTYEHIQTALSSKDGRLPRTYRLFR TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PMPCA peptidase, mitochondrial processing subunit alpha [ Homo sapiens (human) ]
• Official Symbol: PMPCA
• Synonyms: PMPCA; peptidase (mitochondrial processing) alpha; inositol polyphosphate 5 phosphatase, 72 kD, INPP5E; mitochondrial-processing peptidase subunit alpha; Alpha MPP; KIAA0123; P-55; inositol polyphosphate-5-phosphatase, 72 kD; mitochondrial matrix processing protease, alpha subunit; INPP5E; Alpha-MPP; FLJ26258; MGC104197
• Gene ID: 23203
• mRNA Refseq: NM_015160
• Protein Refseq: NP_055975
• MIM: 613036
• UniProt ID: Q10713