| Description : |
The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
80.3 kDa |
| AA Sequence : |
MELADVGAAASSQGVHDQVLPTPNA SSRVIVHVDLDCFYAQVEMISNPEL KDKPLGVQQKYLVVTCNYEARKLGV KKLMNVRDAKEKCPQLVLVNGEDLT RYREMSYKVTELLEEFSPVVERLGF DENFVDLTEMVEKRLQQLQSDELSA VTVSGHVYNNQSINLLDVLHIRLLV GSQIAAEMREAMYNQLGLTGCAGVA SNKLLAKLVSGVFKPNQQTVLLPES CQHLIHSLNHIKEIPGIGYKTAKCL EALGINSVRDLQTFSPKILEKELGI SVAQRIQKLSFGEDNSPVILSGPPQ SFSEEDSFKKCSSEVEAKNKIEELL ASLLNRVCQDGRKPHTVRLIIRRYS SEKHYGRESRQCPIPSHVIQKLGTG NYDVMTPMVDILMKLFRNMVNVKMP FHLTLLSVCFCNLKALNTAKKGLID YYLMPSLSTTSRSGKHSFKMKDTHM EDFPKDKETNRDFLPSGRIESTRTR ESPLDTTNFSKEKDINEFPLCSLPE GVDQEVFKQLPVDIQEEILSGKSRE KFQGKGSVSCPLHASRGVLSFFSKK QMQDIPINPRDHLSSSKQVSSVSPC EPGTSGFNSSSSSYMSSQKDYSYYL DNRLKDERISQGPKEPQGFHFTNSN PAVSAFHSFPNLQSEQLFSRNHTTD SHKQTVATDSHEGLTENREPDSVDE KITFPSDIDPQVFYELPEAVQKELL AEWKRAGSDFHIGHKTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
