Recombinant Human PON1 Protein (2-355 aa), GST-tagged

• Cat.No.: PON1-732H
• Product Overview: Recombinant Human PON1 Protein (2-355 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Cardiovascular. Protein Description: Full Length of Mature Protein.

Specification

• Description: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 66.6 kDa
• Protein length: 2-355 aa
• AA Sequence: AKLIALTLLGMGLALFRNHQSSYQT RLNALREVQPVELPNCNLVKGIETG SEDLEILPNGLAFISSGLKYPGIKS FNPNSPGKILLMDLNEEDPTVLELG ITGSKFDVSSFNPHGISTFTDEDNA MYLLVVNHPDAKSTVELFKFQEEEK SLLHLKTIRHKLLPNLNDIVAVGPE HFYGTNDHYFLDPYLQSWEMYLGLA WSYVVYYSPSEVRVVAEGFDFANGI NISPDGKYVYIAELLAHKIHVYEKH ANWTLTPLKSLDFNTLVDNISVDPE TGDLWVGCHPNGMKIFFYDSENPPA SEVLRIQNILTEEPKVTQVYAENGT VLQGSTVASVYKGKLLIGTVFHKAL YCEL
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: PON1 paraoxonase 1 [ Homo sapiens ]
• Official Symbol: PON1
• Synonyms: PON1; PON; ESA; K-45; PON 1; MVCD5
• Gene ID: 5444
• mRNA Refseq: NM_000446
• Protein Refseq: NP_000437
• UniProt ID: P27169