Recombinant Human potassium channel tetramerization domain containing 5, His-tagged

• Cat.No.: KCTD5-359H
• Product Overview: KCTD5, 1-234aa, Human, His tag, E.coli

Specification

• Description: BTB/POZ domain-containing protein KCTD5, also known as KCTD5, is a 234 amino acid protein that localizes predominantly in the cytoplasm but translocates to the nucleus upon interaction with REP proteins. The expression of KCTD5 was upregulated post-transcriptionally in peripheral blood lymphocytes stimulated through the T-cell receptor. KCTD5 interacted specifically with cullin3, bound ubiquitinated proteins, and formed oligomers through its BTB domain. Recombinant human KCTD5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol,1mM DTT
• Molecular Mass: 28.5 kDa (257aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAENHCE LLSPARGGIG AGLGGGLCRR CSAGLGALAQ RPGSVSKWVR LNVGGTYFLT TRQTLCRDPK SFLYRLCQAD PDLDSDKDET GAYLIDRDPT YFGPVLNYLR HGKLVINKDL AEEGVLEEAE FYNITSLIKL VKDKIRERDS KTSQVPVKHV YRVLQCQEEE LTQMVSTMSD GWKFEQLVSI GSSYNYGNED QAEFLCVVSK ELHNTPYGTA SEPSEKAKIL QERGSRM
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: KCTD5 potassium channel tetramerisation domain containing 5 [ Homo sapiens ]
• Official Symbol: KCTD5
• Synonyms: KCTD5; potassium channel tetramerisation domain containing 5; BTB/POZ domain-containing protein KCTD5; FLJ20040
• Gene ID: 54442
• mRNA Refseq: NM_018992
• Protein Refseq: NP_061865
• MIM: 611285
• UniProt ID: Q9NXV2
• Chromosome Location: 16p13.3
• Function: protein binding; voltage-gated potassium channel activity