Recombinant Human POU2F3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: POU2F3-6682H
• Product Overview: POU2F3 MS Standard C13 and N15-labeled recombinant protein (NP_055167) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 47.4 kDa
• AA Sequence: MVNLESMHTDIKMSGDVADSTDARS TLSQVEPGNDRNGLDFNRQIKTEDL SDSLQQTLSHRPCHLSQGPAMMSGN QMSGLNASPCQDMASLHPLQQLVLV PGHLQSVSQFLLSQTQPGQQGLQPN LLPFPQQQSGLLLPQTGPGLASQAF GHPGLPGSSLEPHLEASQHLPVPKH LPSSGGADEPSDLEELEKFAKTFKQ RRIKLGFTQGDVGLAMGKLYGNDFS QTTISRFEALNLSFKNMCKLKPLLE KWLNDAESSPSDPSVSTPSSYPSLS EVFGRKRKKRTSIETNIRLTLEKRF QDNPKPSSEEISMIAEQLSMEKEVV RVWFCNRRQKEKRINCPVATPIKPP VYNSRLVSPSGSLGPLSVPPVHSTM PGTVTSSCSPGNNSRPSSPGSGLHA SSPTASQNNSKAAVNSASSFNSSGS WYRWNHSTYLHTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: POU2F3 POU class 2 homeobox 3 [ Homo sapiens (human) ]
• Official Symbol: POU2F3
• Synonyms: POU2F3; POU class 2 homeobox 3; POU domain class 2, transcription factor 3; POU domain, class 2, transcription factor 3; Epoc 1; OCT11; PLA 1; Skn 1a; octamer-binding protein 11; transcription factor PLA-1; transcription factor Skn-1; POU domain transcription factor OCT11a; octamer-binding transcription factor 11; PLA1; PLA-1; Epoc-1; OCT-11; OTF-11; Skn-1a; FLJ40063; MGC126698
• Gene ID: 25833
• mRNA Refseq: NM_014352
• Protein Refseq: NP_055167
• MIM: 607394
• UniProt ID: Q9UKI9