Recombinant Human PPM1G, His-tagged
Cat.No. : | PPM1G-1896H |
Product Overview : | Recombinant Human PPM1G protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 191-546aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G [ Homo sapiens ] |
Official Symbol : | PPM1G |
Synonyms : | PPM1G; protein phosphatase, Mg2+/Mn2+ dependent, 1G; protein phosphatase 1G (formerly 2C), magnesium dependent, gamma isoform; protein phosphatase 1G; PP2C; gamma; PP2CG; PP2Cgamma; protein phosphatase 2C; gamma isoform; PP2C-gamma; PP2C, gamma; protein phosphatase 1C; protein phosphatase 2C gamma isoform; protein phosphatase 2C isoform gamma; protein phosphatase magnesium-dependent 1 gamma; protein phosphatase 2, catalytic subunit, gamma isoform; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; PPP2CG; PP2CGAMMA; MGC1675; MGC2870; |
Gene ID : | 5496 |
mRNA Refseq : | NM_177983 |
Protein Refseq : | NP_817092 |
MIM : | 605119 |
UniProt ID : | O15355 |
Chromosome Location : | 2p23.3 |
Pathway : | mRNA processing, organism-specific biosystem; |
Function : | catalytic activity; hydrolase activity; metal ion binding; protein serine/threonine phosphatase activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionResearch is ongoing to explore the therapeutic potential of targeting PPM1G in cancer. Inhibiting or modulating its activity may be a strategy for cancer therapy.
Yes, abnormal expression of PPM1G has been linked to certain cancers, suggesting its potential role as a biomarker or therapeutic target.
While rare, mutations in the PPM1G gene have been reported and may be associated with certain genetic disorders. Further research is needed to understand the implications.
PPM1G is involved in the regulation of DNA repair processes, influencing the repair of damaged DNA and maintaining genomic stability.
PPM1G expression levels may serve as a diagnostic marker for certain diseases, including some cancers, but more studies are required to establish its diagnostic utility.
Customer Reviews (3)
Write a reviewPPM1G protein's utility in protein electron microscopy structure analysis is commendable.
It enables researchers to delve deeper into the intricacies of protein behavior and aids in advancing our knowledge in various fields, such as molecular biology, biochemistry, and structural biology.
It demonstrates excellent performance in ELISA assays, making it an ideal choice for researchers studying protein-protein interactions, antibody detection, or biomarker identification.
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