Recombinant Human PRKG2 Protein (M1-F762), GST tagged
Cat.No. : | PRKG2-0334H |
Product Overview : | Recombinant Human GST-TEV-PRKG2(M1-F762 end) Protein was expressed in Insect cell. |
- Specification
- Gene Information
- Related Products
Description : | Crucial regulator of intestinal secretion and bone growth. Phosphorylates and activates CFTR on the plasma membrane. Plays a key role in intestinal secretion by regulating cGMP-dependent translocation of CFTR in jejunum. Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity. Phosphorylates GRIA1/GLUR1 at Ser-863. Acts as regulator of gene expression and activator of the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2 in mechanically stimulated osteoblasts. Under fluid shear stress, mediates ERK activation and subsequent induction of FOS, FOSL1/FRA1, FOSL2/FRA2 and FOSB that play a key role in the osteoblast anabolic response to mechanical stimulation. |
Source : | Insect cell |
Species : | Human |
Tag : | GST |
Form : | Liquid |
Protein Length : | M1-F762 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | PRKG2 protein kinase, cGMP-dependent, type II [ Homo sapiens (human) ] |
Official Symbol : | PRKG2 |
Synonyms : | PRKG2; protein kinase, cGMP-dependent, type II; cGMP-dependent protein kinase 2; cGKII; PRKGR2; cGK2; cGK 2; cGMP-dependent protein kinase II; |
Gene ID : | 5593 |
mRNA Refseq : | NM_006259 |
Protein Refseq : | NP_006250 |
MIM : | 601591 |
UniProt ID : | Q13237 |
Products Types
◆ Recombinant Protein | ||
PRKG2-0333H | Recombinant Human PRKG2 Protein (M1-F762), Tag Free | +Inquiry |
PRKG2-1768H | Recombinant Human PRKG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRKG2-2623H | Recombinant Human PRKG2 Protein, His-tagged | +Inquiry |
PRKG2-1981H | Recombinant Human PRKG2 Protein, His&GST-tagged | +Inquiry |
PRKG2-4344R | Recombinant Rat PRKG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PRKG2-2849HCL | Recombinant Human PRKG2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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