Recombinant Human Protein Arginine Methyltransferase 3, GST-tagged
Cat.No. : | PRMT3-1617H |
Product Overview : | Recombinant full-length human PRMT3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
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Cat. No. : | PRMT3-1617H |
Description : | PRMT3 is a protein arginine methyltransferase that catalyze the formation of asymmetric N (G),N (G)-dimethylarginine (ADMA) residues in proteins. 40S ribosomal protein S2 is a physiological substrate of PRMT3 and PRMT3 regulates ribosome biosynthesis at a stage beyond pre-rRNA processing. DAL-1 (differentially expressed in adenocarcinoma of the lung)/4.1B is a tumor suppressor gene that can significantly inhibits PRMT3 methylation of cellular substrates. Modulation of post-translational methylation may be an important mechanism through which DAL-1/4.1B affects tumor cell growth. |
Applications : | Western Blot |
Molecular Weight : | 97 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50 mM Tris-HCL, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol, 0.1 mM EDTA. |
Purity : | > 90 % |
Concentration : | 0.1 ug/ul |
Storage : | Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | PRMT3 protein arginine methyltransferase 3 [ Homo sapiens ] |
Official Symbol : | PRMT3 |
Synonyms : | PRMT3; protein arginine methyltransferase 3; HRMT1L3; HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae); Protein arginine N-methyltransferase 3; EC 2.1.1;Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3 |
Gene ID : | 10196 |
mRNA Refseq : | NM_001145166 |
Protein Refseq : | NP_001138638 |
MIM : | 603190 |
UniProt ID : | O60678 |
Chromosome Location : | 11p15.1 |
Function : | metal ion binding; protein-arginine N-methyltransferase activity; transferase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
PRMT3-3003H | Recombinant Human PRMT3 Protein, MYC/DDK-tagged | +Inquiry |
PRMT3-007H | Active Recombinant Human PRMT3 Protein, GST-tagged | +Inquiry |
Prmt3-5132M | Recombinant Mouse Prmt3 Protein, Myc/DDK-tagged | +Inquiry |
PRMT3-4365R | Recombinant Rat PRMT3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRMT3-097H | Recombinant Human PRMT3 Protein, GST-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1855 | PRMT3 Chemiluminescent Assay Kit | +Inquiry |
Kit-1856 | PRMT3 Homogeneous Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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