Recombinant Human Protein Kinase C, Delta, GST-tagged, Active
Cat.No. : | PRKCD-401H |
Product Overview : | Recombinant human full-length PKCdelta was expressed by baculovirus inSf9 cellsusing an N-terminal GST tag. MW=104 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PRKCD-401H |
Description : | Protein kinase C delta (PKCδ) is a member of the protein kinase C (PKC) family of serine-threonine kinases. It is a 79 kd protein kinase that shows strict dependence on the presence of phospholipids, but shows no activation by Ca2+. Phosphatidylinositol is the most potent activator of PKC delta. Northern blot analysis indicated that PKCdelta is widely distributed in almost all the tissues and is a major isoform of PKC expressed in hemopoietic cells. PKCdelta is involved in fundamental cellular functions regulated by diacylglycerols and mimicked by phorbol esters. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | PRKCD protein kinase C, delta [ Homo sapiens ] |
Synonyms : | PRKCD; protein kinase C, delta; MAY1; PKCD; MGC49908; nPKC-delta; Protein kinase C delta type; EC 2.7.11.13; protein kinase C delta VIII |
Gene ID : | 5580 |
mRNA Refseq : | NM_006254 |
Protein Refseq : | NP_006245 |
UniProt ID : | Q05655 |
Chromosome Location : | 3p21.31 |
MIM : | 176977 |
Pathway : | Chemokine signaling pathway; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; GnRH signaling pathway; Neurotrophin signaling pathway; Tight junction; Type II diabetes mellitus; Vascular smooth muscle contraction; Apoptosis; Signalling by NGF |
Function : | ATP binding; calcium-independent protein kinase C activity; enzyme activator activity; enzyme binding; insulin receptor substrate binding; metal ion binding; nucleotide binding; protein C-terminus binding; transferase activity; zinc ion binding |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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