Recombinant Human Protein Tyrosine Phosphatase, Receptor Type, M
Cat.No. : | PTPRM-5469H |
Product Overview : | Recombinant humanPTPRM is expressed in E. coli; it contains the catalytic domain of PTPRM(residues 839-1100) and has a molecular weight of 30.2 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PTPRM-5469H |
Description : | PTPRM is involved inthe control of cell-cell adhesion and the cadherin-catenin complex. It hasalso been shown to bind and recruit RACK1 to thte plasma membrane. Human PTPRMis a receptor protein tyrosine phosphatase containing 1390 amino acids. |
Source : | E. coli |
Species : | Human |
Form : | 25 mMTris-HCl (pH 8.0), 75 mM NaCl, 0.05% Tween-20, 2 mM EDTA, 1 mM DTT and 50%glycerol. Liquid at -20°C. |
Purity : | Greaterthan 95% as determined by Coomassie-stained SDS-PAGE gel. |
Specific Activity : | 1265 U/μg.One unit will hydrolyze 1 nmol of p-nitrophenyl phosphate per minute at pH7.4 and 30°C. Assay buffer: 50 mM HEPES (pH 7.4), 2 mM EDTA, 3 mM DTT, 100 mMNaCl and 50 mM pNPP. |
Applications : | Removal ofphosphates from target substrates. Useful for the study of enzyme kinetics,regulation and for inhibitors screening. |
Storage : | 6 monthsat -20°C. |
Pathways : | Adherens junction;Cell adhesion molecules (CAMs); Nectin adhesion pathway |
Gene Name : | PTPRM protein tyrosinephosphatase, receptor type, M [ Homo sapiens ] |
Official Symbol : | PTPRM |
Synonyms : | PTPRM; proteintyrosine phosphatase, receptor type, M; RPTPM; RPTPU;PTPRL1; hR-PTPu; R-PTP-MU; receptor-type tyrosine-protein phosphatase mu; OTTHUMP00000162329;protein tyrosine phosphatase mu; protein-tyrosine phosphatase mu; proteintyrosine phosphatase, receptor type, mu polypeptid |
Gene ID : | 5797 |
mRNA Refseq : | NM_001105244 |
Protein Refseq : | NP_001098714 |
MIM : | 176888 |
UniProt ID : | P28827 |
Chromosome Location : | 18p11.2 |
Function : | cadherin binding;hydrolase activity; protein binding; protein tyrosine phosphatase activity;receptor activity; transmembrane receptor protein tyrosine phosphataseactivity |
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PTPRM-7017H | Recombinant Human PTPRM , GST-tagged | +Inquiry |
PTPRM-336H | Active Recombinant Human Protein Tyrosine Phosphatase, Receptor Type, M | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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