Recombinant Human PSEN2 Over expression Lysate, C-Myc/DDK-tagged
Cat.No. : | PSEN2-HCL |
Product Overview : | Recombinant Human PSEN2 Over expression Lysate with C-Myc/DDK-tag was expressed in HEK293T. |
- Specification
- Gene Information
- Related Products
Description : | Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified. |
Source : | HEK293T |
Species : | Human |
Tag : | C-Myc/DDK |
Molecular Mass : | 50.1 kDa |
Storage : | Upon receiving, store the sample at -20 centigrade. Avoid repeated freeze-thaw cycles after reconstitution. Lysate samples are stable for 12 months from date of receipt when stored at -20 centigrade. |
Reconstitution : | Lysate samples can be reconstituted with SDS Sample Buffer. |
Shipping : | The lysate can be shipped at ambient temperature. |
Gene Name : | PSEN2 presenilin 2 [ Homo sapiens (human) ] |
Official Symbol : | PSEN2 |
Synonyms : | PSEN2; presenilin 2; AD4; PS2; AD3L; STM2; CMD1V; presenilin-2; AD3LP; AD5; Alzheimer disease 3-like; Alzheimer disease 4; E5-1; PS-2; STM-2; EC 3.4.23.- |
Gene ID : | 5664 |
mRNA Refseq : | NM_012486 |
Protein Refseq : | NP_036618 |
MIM : | 600759 |
UniProt ID : | P49810 |
Products Types
◆ Recombinant Protein | ||
PSEN2-3462R | Recombinant Rhesus Macaque PSEN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSEN2-12H | Recombinant Human PSEN2 Protein(1-87 aa), GST-tagged | +Inquiry |
PSEN2-4418R | Recombinant Rat PSEN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSEN2-5875C | Recombinant Chicken PSEN2 | +Inquiry |
PSEN2-4759R | Recombinant Rat PSEN2 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket