| Description : |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
57.1 kDa |
| AA Sequence : |
MAWAALLGLLAALLLLLLLSRRRTR RPGEPPLDLGSIPWLGYALDFGKDA ASFLTRMKEKHGDIFTILVGGRYVT VLLDPHSYDAVVWEPRTRLDFHAYA IFLMERIFDVQLPHYSPSDEKARMK LTLLHRELQALTEAMYTNLHAVLLG DATEAGSGWHEMGLLDFSYSFLLRA GYLTLYGIEALPRTHESQAQDRVHS ADVFHTFRQLDRLLPKLARGSLSVG DKDHMCSVKSRLWKLLSPARLARRA HRSKWLESYLLHLEEMGVSEEMQAR ALVLQLWATQGNMGPAAFWLLLFLL KNPEALAAVRGELESILWQAEQPVS QTTTLPQKVLDSTPVLDSVLSESLR LTAAPFITREVVVDLAMPMADGREF NLRRGDRLLLFPFLSPQRDPEIYTD PEVFKYNRFLNPDGSEKKDFYKDGK RLKNYNMPWGAGHNHCLGRSYAVNS IKQFVFLVLVHLDLELINADVEIPE FDLSRYGFGLMQPEHDVPVRYRIRP TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
