Recombinant Human PTHLH, His-tagged
Cat.No. : | PTHLH-112H |
Product Overview : | Recombinant Human PTHLH(Ala37-Arg175) fussed with 6His tag at C-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Parathyroid Hormone-Related protein (PTHRP) is a member of the parathyroid hormone family. PTHRP is known as a potent inhibitor of chondrocyte maturation. PTHRP is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. PTHRP also regulates epithelial-mesenchymal interactions during the formation of the mammary glands. During endochondral bone development, PTHRP plays a major role in suppressing the onset of hypertrophic differentiation. Defects in PTHRP are the cause of Brachydactyly Type E2. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 |
AA Sequence : | MAVSEHQLLHDKGKSIQDLRRRFFL HHLIAEIHTAEIRATSEVSPNSKPS PNTKNHPVRFGSDDE GRYLTQETNKVETYKEQPLKTPGKK KKGKPGKRKEQEKKKRRTRSAWLDS GVTGSGLEGDHLSDT STTSLELDSRLEHHHHHH |
Endotoxin : | Less than 0.1 ng/µg (1 IEU/µg). |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | PTHLH parathyroid hormone-like hormone [ Homo sapiens ] |
Official Symbol : | PTHLH |
Synonyms : | HHM; PLP; BDE2; PTHR; PTHRP; parathyroid hormone-related protein; PTH-Rp; PTH-related protein; osteostatin; parathyroid hormone-like hormone preproprotein; parathyroid hormone-like related protein |
Gene ID : | 5744 |
mRNA Refseq : | NM_002820 |
Protein Refseq : | NP_002811 |
MIM : | 168470 |
UniProt ID : | P12272 |
Chromosome Location : | 12p12.1-p11.2 |
Pathway : | Class B/2 (Secretin family receptors), organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem |
Function : | hormone activity; peptide hormone receptor binding |
Products Types
◆ Recombinant Protein | ||
PTHLH-3943H | Recombinant Human PTHLH Protein, His (Fc)-Avi-tagged | +Inquiry |
PTHLH-3513R | Recombinant Rhesus Macaque PTHLH Protein, His (Fc)-Avi-tagged | +Inquiry |
Pthlh-5226M | Recombinant Mouse Pthlh Protein, Myc/DDK-tagged | +Inquiry |
Pthlh-2830R | Recombinant Rat Pthlh Protein, His-tagged, KLH Conjugated | +Inquiry |
PTHLH-4480R | Recombinant Rat PTHLH Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PTHLH-2701HCL | Recombinant Human PTHLH 293 Cell Lysate | +Inquiry |
PTHLH-2703HCL | Recombinant Human PTHLH 293 Cell Lysate | +Inquiry |
PTHLH-2702HCL | Recombinant Human PTHLH 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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