Recombinant Human PTPRG
Cat.No. : | PTPRG-30355TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 801-1147 of Human PTP gamma, containing the catalytic domain and with an N terminal properitary tag. M.Wt 65 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. |
Source : | E. coli |
Tissue specificity : | Found in a variety of tissues. |
Biological activity : | 10 U/ug. One unit will hydrolyze 1 nmol p-nitrophenyl phosphateper minute at pH 7.4 and 30C. Assay buffer: 50 mM HEPES, pH 7.4, 2 mM EDTA, 3mM DTT, 100 mM NaCl, 50 mM pNPP. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 75mM Sodium chloride, 25mM Tris HCl, 2mM EDTA, 10mM Glutathione, 1mM DTT, pH 8.0 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.Contains 1 alpha-carbonic anhydrase domain.Contains 1 fibronectin type-III domain.Contains 2 tyrosine-protein phosphatase domains. |
Gene Name : | PTPRG protein tyrosine phosphatase, receptor type, G [ Homo sapiens ] |
Official Symbol : | PTPRG |
Synonyms : | PTPRG; protein tyrosine phosphatase, receptor type, G; PTPG; receptor-type tyrosine-protein phosphatase gamma; RPTPG; |
Gene ID : | 5793 |
mRNA Refseq : | NM_002841 |
Protein Refseq : | NP_002832 |
MIM : | 176886 |
Uniprot ID : | P23470 |
Chromosome Location : | 3p21-p14 |
Function : | hydrolase activity; identical protein binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity; |
Products Types
◆ Recombinant Protein | ||
PTPRG-0841H | Recombinant Human PTPRG Protein (P820-N1130), Tag Free | +Inquiry |
PTPRG-0842H | Recombinant Human PTPRG Protein (P820-N1130), His tagged | +Inquiry |
PTPRG-2063H | Recombinant Human PTPRG, His-tagged | +Inquiry |
PTPRG-5887C | Recombinant Chicken PTPRG | +Inquiry |
PTPRG-459H | Recombinant Human PTPRG, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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