Recombinant Human PYCARD, GST-tagged
Cat.No. : | PYCARD-29108H |
Product Overview : | Human PYCARD full-length ORF ( AAH13569.2, 1 a.a. - 149 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 42.13 kDa |
AA Sequence : | MDALDLTDKLVSFYLETYGAELTAN VLRDMGLQEMAGQLQAATHQGSGAA PAGIQAPPQSAAKPGLHFIDQHRAA LIARVTNVEWLLDALYGKVLTDEQY QAVRAEPTNPSKMRKLFNFTPAWNW TCKDLLLQALRESQSYLVEDLERS |
Applications : | Enzyme-linked Immunoabsorbent Assay, Western Blot, Antibody Production, Protein Array. |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | PYCARD PYD and CARD domain containing [ Homo sapiens (human) ] |
Official Symbol : | PYCARD |
Synonyms : | ASC; TMS; TMS1; CARD5; TMS-1 |
Gene ID : | 29108 |
Protein Refseq : | AAH13569.2 |
MIM : | 606838 |
Chromosome Location : | 16p11.2 |
Pathway : | Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Influenza A, organism-specific biosystem |
Function : | Pyrin domain binding; ion channel binding |
Products Types
◆ Recombinant Protein | ||
PYCARD-1814H | Recombinant Human PYCARD Protein, His (Fc)-Avi-tagged | +Inquiry |
PYCARD-080H | Recombinant Human PYCARD Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
PYCARD-01H | Recombinant Human PYCARD Protein, Myc/DDK-tagged | +Inquiry |
PYCARD-3535R | Recombinant Rhesus Macaque PYCARD Protein, His (Fc)-Avi-tagged | +Inquiry |
PYCARD-9047Z | Recombinant Zebrafish PYCARD | +Inquiry |
◆ Lysates | ||
PYCARD-2650HCL | Recombinant Human PYCARD 293 Cell Lysate | +Inquiry |
PYCARD-2648HCL | Recombinant Human PYCARD 293 Cell Lysate | +Inquiry |
PYCARD-2649HCL | Recombinant Human PYCARD 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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