Recombinant Human RAC1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RAC1-5665H
• Product Overview: RAC1 MS Standard C13 and N15-labeled recombinant protein (NP_061485) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 23.3 kDa
• AA Sequence: MQAIKCVVVGDGAVGKTCLLISYTT NAFPGEYIPTVFDNYSANVMVDGKP VNLGLWDTAGQEDYDRLRPLSYPQT VGETYGKDITSRGKDKPIADVFLIC FSLVSPASFENVRAKWYPEVRHHCP NTPIILVGTKLDLRDDKDTIEKLKE KKLTPITYPQGLAMAKEIGAVKYLE CSALTQRGLKTVFDEAIRAVLCPPP VKKRKRKCLLLTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RAC1 Rac family small GTPase 1 [ Homo sapiens (human) ]
• Official Symbol: RAC1
• Synonyms: RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1; p21 Rac1; Rac 1; TC 25; ras-like protein TC25; cell migration-inducing gene 5 protein; MIG5; Rac-1; TC-25; p21-Rac1; MGC111543
• Gene ID: 5879
• mRNA Refseq: NM_018890
• Protein Refseq: NP_061485
• MIM: 602048
• UniProt ID: P63000

Reviews

05/03/2022

RAC1 protein is highly recommended for researchers and scientists due to its exceptional performance in ELISA assays.

12/20/2021

Its reliability in ELISA makes it a trusted tool for quantitative and qualitative protein analysis.

12/22/2018

With its superior binding affinity and specificity, RAC1 protein enables accurate and reliable detection of target analytes in various biological samples.

Q&As

Are there any ongoing clinical trials targeting RAC1 for therapeutic purposes?

Yes, there are clinical trials investigating the efficacy of RAC1-targeted therapies in various diseases, including cancer and inflammatory disorders.

How does RAC1 influence the progression of diabetic complications?

RAC1 activation is implicated in the development of diabetic complications, particularly in the context of vascular dysfunction and diabetic nephropathy.

Can RAC1 be a biomarker for neurodegenerative diseases?

Research suggests that altered RAC1 expression and activity may serve as a biomarker for certain neurodegenerative diseases.

In what ways does RAC1 impact neuronal function, and how does this relate to neurological disorders?

RAC1 is crucial for neurite outgrowth and synaptic plasticity, and its dysregulation has been implicated in neurological disorders, suggesting a potential target for therapeutic interventions.

How does RAC1 contribute to cardiovascular diseases, and what are the potential therapeutic interventions?

RAC1 is involved in vascular smooth muscle cell migration, and its dysregulation is associated with cardiovascular diseases. Targeting RAC1 may offer therapeutic benefits in such cases.