Recombinant Human Ras-related C3 Botulinum Toxin Substrate 1
Cat.No. : | RAC1-189H |
Product Overview : | Recombinant Human Ras-Related C3 Botulinum Toxin substrate 1 produced inE.Coliis a single, non-glycosylated polypeptide chain. The protein contains 192 amino acids and has a molecular mass of 21.4 kDa. |
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Cat. No. : | RAC1-189H |
Description : | RAC1 is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. RAC-1 regulates the actin cytoskeleton but also other cellular processes. RAC1 have been shown to be involved in the regulation of cell-cell adhesion. |
Source : | E.Coli. |
Amino Acid Sequence : | MQAIKCVVVGDGAVGKTCLLISYTT NAFPGEYIPTVFDNYSANVMVDGKP VNLGLWDTAQEDYDRLRPLSYPQTD VFLICFSLVSPASFENVRAKWYPEV RHHCPNTPIILVGTKLDLRDDKDTI EKLKEKKLTPITYPQGLAMAKEIGA VKYLECSALTQRGLKTVFDEAIRAV LCP PPVKKRKRKCLLL. |
Physical Appearance : | Sterile Filtered colorless solution. |
Formulation : | The protein solution (1mg/ml) cotains 20mM Tris-HCl pH7.5, 2mM EDTA and 1mM DTT. |
Purity : | Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Stability : | RAC1 although stable 14°Cfor 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name : | RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) [ Homo sapiens ] |
Synonyms : | RAC1; MGC111543; MIG5; TC-25; PAK1; TC25; P21-RAC1; RAC-1; p21-Rac1;Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); RAS-like protein; Ras-related C3 botulinum toxin substrate 1; rho family; small GTP binding protein Rac1; Ras-related C3 botulinum toxin substrate 1; Cell migration-inducing gene 5 protein; Ras-like protein TC25; migration-inducing gene 5; migration-inducing protein 5; ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 isoform Rac1; ras-related C3 botulinum toxin substrate 1 isoform Rac1b; rho family, small GTP binding protein Rac1 |
Gene ID : | 5879 |
mRNA Refseq : | NM_006908 |
Protein Refseq : | NP_008839 |
MIM : | 602048 |
UniProt ID : | P63000 |
Chromosome Location : | 7p22 |
Pathway : | Adherens junction; Amyotrophic lateral sclerosis (ALS); Axon guidance; B cell receptor signaling pathway; Chemokine signaling pathway; Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Focal adhesion; Leukocyte transendothelial migration; MAPK signaling pathway; Natural killer cell mediated cytotoxicity; Neurotrophin signaling pathway; Pancreatic cancer; Regulation of actin cytoskeleton; Renal cell carcinoma; Toll-like receptor signaling pathway; VEGF signaling pathway; Wnt signaling pathway |
Function : | GTP binding; GTP-dependent protein binding; GTPase activity; enzyme binding; nucleotide binding |
Products Types
◆ Recombinant Protein | ||
RAC1-445H | Recombinant Human RAC1 Protein, MYC/DDK-tagged | +Inquiry |
RAC1-1845H | Recombinant Human RAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
RAC1-7379M | Recombinant Mouse RAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rac1-5344M | Recombinant Mouse Rac1 Protein, Myc/DDK-tagged | +Inquiry |
RAC1-4567R | Recombinant Rat RAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
RAC1-712HCL | Recombinant Human RAC1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, there are clinical trials investigating the efficacy of RAC1-targeted therapies in various diseases, including cancer and inflammatory disorders.
RAC1 activation is implicated in the development of diabetic complications, particularly in the context of vascular dysfunction and diabetic nephropathy.
Research suggests that altered RAC1 expression and activity may serve as a biomarker for certain neurodegenerative diseases.
RAC1 is crucial for neurite outgrowth and synaptic plasticity, and its dysregulation has been implicated in neurological disorders, suggesting a potential target for therapeutic interventions.
RAC1 is involved in vascular smooth muscle cell migration, and its dysregulation is associated with cardiovascular diseases. Targeting RAC1 may offer therapeutic benefits in such cases.
Customer Reviews (3)
Write a reviewRAC1 protein is highly recommended for researchers and scientists due to its exceptional performance in ELISA assays.
Its reliability in ELISA makes it a trusted tool for quantitative and qualitative protein analysis.
With its superior binding affinity and specificity, RAC1 protein enables accurate and reliable detection of target analytes in various biological samples.
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