Recombinant Human RBP3 Protein, His-tagged
Cat.No. : | RBP3-35H |
Product Overview : | Recombinant Human RBP3 Protein (Gly18-Leu1247) is produced by Human Cells expression system. This protein is fused with a 6His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
- Download
Description : | Retinol-binding proteins (RBP) are a family of proteins with diverse functions. They are carrier proteins that bind retinol. Retinol and retinoic acid play crucial roles in the modulation of gene expression and overall development of an embryo. However, deficit or excess of either one of these substances can cause early embryo mortality or developmental malformations. Regulation of transport and metabolism of retinol necessary for a successful pregnancy is accomplished via RBP. Retinol binding proteins have been identified within the uterus, embryo, and extraembryonic tissue of the bovine, ovine, and porcine, clearly indicating that RBP plays a role in proper retinol exposure to the embryo and successful transport at the maternal-fetal interface. |
Source : | Human Cells |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Protein length : | Gly18-Leu1247 |
AA Sequence : | GPTHLFQPSLVLDMAKVLLDNYCFP ENLLGMQEAIQQAIKSHEILSISDP QTLASVLTAGVQSSL NDPRLVISYEPSTPEPPPQVPALTS LSEEELLAWLQRGLRHEVLEGNVGY LRVDSVPGQEVLSMM GEFLVAHVWGNLMGTSALVLDLRHC TGGQVSGIPYIISYLHPGNTILHVD TIYNRPSNTTTEIWT LPQVLGERYGADKDVVVLTSSQTRG VAEDIAHILKQMRRAIVVGERTGGG ALDLRKLRIGESDFF FTVPVSRSLGPLGGGSQTWEGSGVL PCVGTPAEQALEKALAILTLRSALP GVVHCLQEVLKDYYT LVDRVPTLLQHLASMDFSTVVSEED LVTKLNAGLQAASEDPRLLVRAIGP TETPSWPAPDAAAED SPGVAPELPEDEAIRQALVDSVFQV SVLPGNVGYLRFDSFADASVLGVLA PYVLRQVWEPLQDTE HLIMDLRHNPGGPSSAVPLLLSYFQ GPEAGPVHLFTTYDRRTNITQEHFS HMELPGPRYSTQRGV YLLTSHRTATAAEEFAFLMQSLGWA TLVGEITAGNLLHTRTVPLLDTPEG SLALTVPVLTFIDNH GEAWLGGGVVPDAIVLAEEALDKAQ EVLEFHQSLGALVEGTGHLLEAHYA RPEVVGQTSALLRAK LAQGAYRTAVDLESLASQLTADLQE VSGDHRLLVFHSPGELVVEEAPPPP PAVPSPEELTYLIEA LFKTEVLPGQLGYLRFDAMAELETG KAVGPQLVRLVWQQLVDTAALVIDL RYNPGSYSTAIPLLC SYFFEAEPRQHLYSVFDRATSKVTE VWTLPQVAGQRYGSHKDLYILMSHT SGSAAEAFAHTMQDL QRATVIGEPTAGGALSVGIYQVGSS PLYASMPTQMAMSATTGKAWDLAGV EPDITVPMSEALSIA QDIVALRAKVPTVLQTAGKLVADNY ASAELGAKMATKLSGLQSRYSRVTS EVALAEILGADLQML SGDPHLKAAHIPENAKDRIPGIVPM QIPSPEVFEELIKFSFHTNVLEDNI GYLRFDMFGDGELLT QVSRLLVEHIWKKIMHTDAMIIDMR FNIGGPTSSIPILCSYFFDEGPPVL LDKIYSRPDDSVSEL WTHAQVVGERYGSKKSMVILTSSVT AGTAEEFTYIMKRLGRALVIGEVTS GGCQPPQTYHVDDTN LYLTIPTARSVGASDGSSWEGVGVT PHVVVPAEEALARAKEMLQHNQLRV KRSPGLQDHLHHHHH H |
Endotoxin : | < 0.1 ng/µg (1 IEU/µg) as determined by LAL test. |
Purity : | > 95% as determined by reducing SDS-PAGE. |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | RBP3 retinol binding protein 3, interstitial [ Homo sapiens ] |
Official Symbol : | RBP3 |
Synonyms : | RBP3; D10S64; D10S65; D10S66; IRBP; RBPI; |
Gene ID : | 5949 |
mRNA Refseq : | NM_002900 |
Protein Refseq : | NP_002891 |
MIM : | 180290 |
UniProt ID : | P10745 |
Products Types
◆ Recombinant Protein | ||
Rbp3-5426M | Recombinant Mouse Rbp3 Protein, Myc/DDK-tagged | +Inquiry |
RBP3-1865H | Recombinant Human RBP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
RBP3-715H | Recombinant Human RBP3 Protein, MYC/DDK-tagged | +Inquiry |
RBP3-1501B | Recombinant Bovine RBP3 Protein (633-1231 aa), His-tagged | +Inquiry |
RBP3-2329B | Recombinant Bovine RBP3 Protein (933-1231 aa), GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionRBP3 contributes to the efficient transport and delivery of retinoids to photoreceptor cells, facilitating their uptake for visual processes.
Potential therapeutic strategies targeting RBP3 could address vision-related disorders involving retinoid metabolism, making it a promising focus for drug development.
RBP3 interacts with binding partners, including retinoids like 11-cis-retinal, influencing its role in retinoid transport and uptake.
RBP3 is predominantly localized within the retina, specifically in photoreceptor cells and the retinal pigment epithelium (RPE).
RBP3 actively regulates retinoid homeostasis and participates in the visual cycle, critical for maintaining optimal visual function.
Retinol-Binding Protein 3 (RBP3) plays a crucial role in supporting visual function and regulating retinoid metabolism.
Dysregulation or abnormal expression of RBP3 is associated with vision-related disorders such as retinitis pigmentosa.
Customer Reviews (3)
Write a reviewGel electrophoresis consistently displayed well-defined bands, affirming the product's purity and reliability.
Replicating results underscored the reliability and relevance of the product's effects.
The user-friendly design of the product made it accessible to researchers with varying levels of expertise.
Ask a Question for All RBP3 Products
Required fields are marked with *
My Review for All RBP3 Products
Required fields are marked with *
Inquiry Basket