Recombinant Human RCAN family member 3, His-tagged
Cat.No. : | RCAN3-372H |
Product Overview : | RCAN3, 56-241aa, Human, His tag, E.coli |
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Description : | Calcipressin-3, also known as RCAN3, is a 241 amino acid protein that potentially is involved in central nervous system development. RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Overexpression of calcipressin-3 results in inhibition of calcineurin activity towards the nuclear factor of activated T-cells (NFAT) transcription factors and also downregulates NFAT-dependent cytokine gene expression in activated Jurkat T-cells. Highest expression occurs in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Recombinant human RCAN3 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M Urea, 20% glycerol, 0.2M NaCl |
Molecular Mass : | 23.5 kDa (209aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSEAVFEAR EQKERFEALF TIYDDQVTFQ LFKSFRRVRI NFSKPEAAAR ARIELHETDF NGQKLKLYFA QVQMSGEVRD KSYLLPPQPV KQFLISPPAS PPVGWKQSED AMPVINYDLL CAVSKLGPGE KYELHAGTES TPSVVVHVCE SETEEEEETK NPKQKIAQTR RPDPPTAALN EPQTFDCAL |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | RCAN3 RCAN family member 3 [ Homo sapiens ] |
Official Symbol : | RCAN3 |
Synonyms : | RCAN3; RCAN family member 3; Down syndrome critical region gene 1 like 2 , DSCR1L2; calcipressin-3; regulator of calcineurin 3; Down syndrome candidate region 1-like 2; Down syndrome critical region gene 1-like 2; down syndrome candidate region 1-like protein 2; myocyte-enriched calcineurin-interacting protein 3; RCN3; MCIP3; hRCN3; DSCR1L2; |
Gene ID : | 11123 |
mRNA Refseq : | NM_001251977 |
Protein Refseq : | NP_001238906 |
MIM : | 605860 |
UniProt ID : | Q9UKA8 |
Chromosome Location : | 1p35.3-p33 |
Function : | RNA binding; nucleotide binding; troponin I binding; |
Products Types
◆ Recombinant Protein | ||
RCAN3-7494M | Recombinant Mouse RCAN3 Protein, His (Fc)-Avi-tagged | +Inquiry |
RCAN3-4032H | Recombinant Human RCAN3 Protein, GST-tagged | +Inquiry |
Rcan3-5434M | Recombinant Mouse Rcan3 Protein, Myc/DDK-tagged | +Inquiry |
RCAN3-14028M | Recombinant Mouse RCAN3 Protein | +Inquiry |
RCAN3-2228H | Recombinant Human RCAN3, GST-tagged | +Inquiry |
◆ Lysates | ||
RCAN3-2448HCL | Recombinant Human RCAN3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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