Recombinant Human RCAN2, His-tagged
Cat.No. : | RCAN2-28376TH |
Product Overview : | Recombinant full length Human DSCR1L1 with an N terminal His tag; 217 amino acids with tag; Predicted MWt 24.1 kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Protein length : | 197 amino acids |
Conjugation : | HIS |
Molecular Weight : | 24.100kDa inclusive of tags |
Source : | E. coli |
Tissue specificity : | Expressed in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas. |
Form : | Liquid |
Purity : | by SDS-PAGE |
Storage buffer : | pH: 8.00Constituents:20% Glycerol, 0.02% DTT, 0.32% Tris HCl, 1.17% Sodium chloride |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MPAPSMDCDV STLVACVVDV EVFTNQEVKE KFEGLFRTYD DCVTFQLFKS FRRVRINFSN PKSAARARIE LHETQFRGKK LKLYFAQVQT PETDGDKLHL APPQPAKQFL ISPPSSPPVG WQPINDATPV LNYDLLYAVA KLGPGEKYEL HAGTESTPSV VVHVCDSDIE EEEDPKTSPK PKIIQTRRPG LPPSVSN |
Sequence Similarities : | Belongs to the RCAN family. |
Gene Name : | RCAN2 regulator of calcineurin 2 [ Homo sapiens ] |
Official Symbol : | RCAN2 |
Synonyms : | RCAN2; regulator of calcineurin 2; Down syndrome critical region gene 1 like 1 , DSCR1L1; calcipressin-2; ZAKI 4; |
Gene ID : | 10231 |
mRNA Refseq : | NM_005822 |
Protein Refseq : | NP_005813 |
MIM : | 604876 |
Uniprot ID : | Q14206 |
Chromosome Location : | 6p12.3 |
Pathway : | Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; Role of Calcineurin-dependent NFAT signaling in lymphocytes, organism-specific biosystem; |
Function : | nucleotide binding; protein phosphatase 2B binding; |
Products Types
◆ Recombinant Protein | ||
RCAN2-713H | Recombinant Human RCAN2 Protein, GST/His-tagged | +Inquiry |
RCAN2-4031H | Recombinant Human RCAN2 Protein, GST-tagged | +Inquiry |
RCAN2-4632R | Recombinant Rat RCAN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
RCAN2-4973R | Recombinant Rat RCAN2 Protein | +Inquiry |
RCAN2-4750H | Recombinant Human Regulator Of Calcineurin 2, His-tagged | +Inquiry |
◆ Lysates | ||
RCAN2-2449HCL | Recombinant Human RCAN2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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