Recombinant Human RELN Protein, His-tagged

• Cat.No.: RELN-2651H
• Product Overview: Recombinant Human RELN Protein (Asp2978-Val3373) with a N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 47.8 kDa
  Accurate Molecular Mass: 46 kDa
• Protein length: Asp2978-Val3373
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: RELN reelin [ Homo sapiens (human) ]
• Official Symbol: RELN
• Synonyms: RELN; reelin; PRO1598; RL; LIS2
• Gene ID: 5649
• mRNA Refseq: NM_005045
• Protein Refseq: NP_005036
• MIM: 600514
• UniProt ID: P78509