Recombinant Human REST Corepressor 1, His-tagged

• Cat.No.: RCOR1-1852H
• Product Overview: Recombinant human RCOR1 protein (a.a. 305-end), fused to His-tag at N-terminus, was expressed inE.coliexpression system, 20 kDa.

Specification

• Cat. No.: RCOR1-1852H
• Description: REST corepressor 1 is a protein that in humans is encoded by the RCOR1 gene. The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression.
• Source: E.coli.
• Purity: > 60%.
• Formulation: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, and 10% glycerol.
• Application: Useful for the stimulation of LSD1 enzyme activity.
• Storage: >6 months at –80°C.
• Pathways: Huntington"s disease

Gene Information

• Gene Name: RCOR1 REST corepressor 1 [ Homo sapiens ]
• Synonyms: RCOR1; REST corepressor 1; RCOR; COREST; KIAA0071; REST corepressor; Protein CoREST
• Gene ID: 23186
• mRNA Refseq: NM_015156
• Protein Refseq: NP_055971
• MIM: 607675
• UniProt ID: Q9UKL0
• Chromosome Location: 14q32.31
• Function: DNA binding; protein binding

Reviews

05/22/2020

Such dedicated support makes me feel confident in my choice of using the RCOR1 protein for my experiments.

01/16/2019

I am highly impressed with the RCOR1 protein as it is of exceptionally high quality, and I am confident that it will perfectly meet the specific requirements of my experiments.

06/21/2016

With their extensive knowledge and expertise, I am assured that any challenges or issues I may encounter during my research will be efficiently resolved.

Q&As

What are the potential limitations of using RCOR1 protein as a clinical biomarker?

Potential limitations include the need for standardized assays, variability in protein expression levels, and the influence of confounding factors on its levels.

Are there any genetic variations in the RCOR1 gene that impact its clinical relevance?

Yes, genetic variations in the RCOR1 gene have been associated with susceptibility to certain neurodegenerative and neurodevelopmental disorders.

How is RCOR1 protein linked to neurodevelopmental disorders?

Dysregulation of RCOR1 protein has been associated with neurodevelopmental disorders such as autism spectrum disorders and intellectual disabilities.

How does RCOR1 protein interact with other proteins in the context of clinical applications?

RCOR1 protein interacts with various transcription factors and epigenetic regulators, and understanding these interactions is crucial for its clinical relevance.

Can RCOR1 protein be used for personalized medicine in neurology?

There is emerging research into using RCOR1 protein profiles for personalized treatment strategies in neurology, especially for patients with neurodegenerative and neurodevelopmental conditions.