Recombinant Human RFK protein, His-tagged

• Cat.No.: RFK-8617H
• Product Overview: Recombinant Human RFK protein(Q969G6)(Met1-His155), fused with His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: Supplied as sterile 20mM Tris, 10% glycerol, pH 8.0Please contact us for any concerns or special requirements.Please refer to the specific buffer information in the hard copy of CoA.
• Molecular Mass: The recombinant human RFK consists of 170 amino acids and predicts a molecular mass of 19.5 KDa. It migrates as an approximately 20 KDa band in SDS-PAGE under reducing conditions.
• Protein Length: Met1-His155
• Purity: > 90 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: RFK riboflavin kinase [ Homo sapiens ]
• Official Symbol: RFK
• Synonyms: RFK; riboflavin kinase; FLJ11149; RIFK; flavokinase; 0610038L10Rik; ATP:riboflavin 5-phosphotransferase; RP11-422N19.2
• Gene ID: 55312
• mRNA Refseq: NM_018339
• Protein Refseq: NP_060809
• MIM: 613010
• UniProt ID: Q969G6

Reviews

01/13/2020

I highly recommend the RFK protein for various experimental applications.

03/26/2018

It has demonstrated outstanding performance in ELISA, providing reliable and precise results.

08/29/2017

It has been invaluable in protein electron microscopy structure analysis, facilitating detailed investigations and yielding valuable insights.

Q&As

Can RFK protein be a therapeutic target in drug development?

Yes, RFK protein modulation may hold potential for therapeutic intervention in diseases related to its deficiency or dysregulation.

In what other areas of medicine is RFK protein relevant?

RFK protein's involvement in cellular metabolism makes it relevant in fields such as oncology, neurology, and mitochondrial disorders.

Are there any known side effects or risks associated with RFK protein-targeted therapies?

Generally, riboflavin supplementation is considered safe; however, high doses might lead to minor side effects like diarrhea or urine discoloration.

What are the treatment approaches for RFK protein-related disorders?

Treatment primarily involves riboflavin supplementation, aiming to restore adequate levels of active FMN and address the underlying deficiency.

How does the understanding of RFK protein aid in personalized medicine?

Understanding RFK protein variants or deficiencies helps in tailoring riboflavin supplementation and treatments for individuals with specific genetic profiles or conditions.