Recombinant Human RFWD2 protein, MYC/DDK-tagged
Cat.No. : | RFWD2-186H |
Product Overview : | Recombinant Human RFWD2, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
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Description : | RFWD2 played an important role in many functions. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 80.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Publication : |
Imaging and kinetics of the bimolecular complex formed by the tumor suppressor p53 with ubiquitin ligase COP1 as studied by atomic force microscopy and surface plasmon resonance (2018)
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Gene Name : | RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase [ Homo sapiens ] |
Official Symbol : | RFWD2 |
Synonyms : | RFWD2; ring finger and WD repeat domain 2, E3 ubiquitin protein ligase; ring finger and WD repeat domain 2; E3 ubiquitin-protein ligase RFWD2; COP1; FLJ10416; RNF200; hCOP1; RING finger protein 200; putative ubiquitin ligase COP1; RING finger and WD repeat domain protein 2; constitutive photomorphogenic protein (COP1); constitutive photomorphogenesis protein 1 homolog; RP11-318C24.3; |
Gene ID : | 64326 |
mRNA Refseq : | NM_022457 |
Protein Refseq : | NP_071902 |
MIM : | 608067 |
UniProt ID : | Q8NHY2 |
Chromosome Location : | 1q25.1-q25.2 |
Pathway : | Autodegradation of the E3 ubiquitin ligase COP1, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; G1/S DNA Damage Checkpoints, organism-specific biosystem; Stabilization of p53, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem; |
Function : | ligase activity; metal ion binding; protein binding; zinc ion binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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