Recombinant Human RGS10, His-tagged
Cat.No. : | RGS10-30741TH |
Product Overview : | Recombinant full length Human RGS10, Isoform 3 with an N terminal His tag; 205 amino acids with the tag; mwt: 23.7kDa. |
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Description : | Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. |
Protein length : | 181 amino acids |
Conjugation : | HIS |
Molecular Weight : | 23.700kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MGSHNVLFWLACED FKKMQDKTQM QEKAKEIYMT FLSSKASSQV NVEGQSRLNE KILEEPHPLM FQKLQDQIFN LMKYDSYSRF LKSDLFLKHK RTEEEEEDLP DAQTAAKRAS RIYNT |
Sequence Similarities : | Contains 1 RGS domain. |
Gene Name : | RGS10 regulator of G-protein signaling 10 [ Homo sapiens ] |
Official Symbol : | RGS10 |
Synonyms : | RGS10; regulator of G-protein signaling 10; regulator of G protein signalling 10; |
Gene ID : | 6001 |
mRNA Refseq : | NM_001005339 |
Protein Refseq : | NP_001005339 |
MIM : | 602856 |
Uniprot ID : | O43665 |
Chromosome Location : | 10q25 |
Pathway : | Calcium Regulation in the Cardiac Cell, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem; |
Function : | GTPase activator activity; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
Rgs10-5490M | Recombinant Mouse Rgs10 Protein, Myc/DDK-tagged | +Inquiry |
RGS10-3599H | Recombinant Human RGS10, His-tagged | +Inquiry |
RGS10-3690R | Recombinant Rhesus Macaque RGS10 Protein, His (Fc)-Avi-tagged | +Inquiry |
RGS10-2274H | Recombinant Human RGS10, GST-tagged | +Inquiry |
Rgs10-8184M | Recombinant Mouse Rgs10 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
RGS10-2386HCL | Recombinant Human RGS10 293 Cell Lysate | +Inquiry |
RGS10-2385HCL | Recombinant Human RGS10 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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