Recombinant Human RGS14 Protein (P2-L566), Tag Free
Cat.No. : | RGS14-1007H |
Product Overview : | Recombinant Human GG-RGS14(human) (P2-L566 end) Protein was expressed in E. coli. |
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Description : | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o)-alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation; a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division. Required for the nerve growth factor (NGF)-mediated neurite outgrowth. Involved in stress resistance. May be involved in visual memory processing capacity and hippocampal-based learning and memory. |
Source : | E. coli |
Species : | Human |
Tag : | No tag |
Form : | Liquid |
Protein Length : | P2-L566 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | RGS14 regulator of G-protein signaling 14 [ Homo sapiens (human) ] |
Official Symbol : | RGS14 |
Synonyms : | RGS14; regulator of G-protein signaling 14; regulator of G protein signalling 14; regulator of G-protein signalling 14; |
Gene ID : | 10636 |
mRNA Refseq : | NM_006480 |
Protein Refseq : | NP_006471 |
MIM : | 602513 |
UniProt ID : | O43566 |
Products Types
◆ Recombinant Protein | ||
RGS14-4674R | Recombinant Rat RGS14 Protein, His (Fc)-Avi-tagged | +Inquiry |
RGS14-7564M | Recombinant Mouse RGS14 Protein, His (Fc)-Avi-tagged | +Inquiry |
RGS14-1008H | Recombinant Human RGS14 Protein (P2-L566), His tagged | +Inquiry |
Rgs14-5493M | Recombinant Mouse Rgs14 Protein, Myc/DDK-tagged | +Inquiry |
RGS149388H | Recombinant Human RGS14 (302-566)_RBD domain Protein | +Inquiry |
◆ Lysates | ||
RGS14-1502HCL | Recombinant Human RGS14 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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