Recombinant Human RIN2 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | RIN2-1040H |
Product Overview : | RIN2 MS Standard C13 and N15-labeled recombinant protein (NP_061866) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 100 kDa |
AA Sequence : | MTAWTMGARGLDKRGSFFKLIDTIA SEIGELKQEMVRTDVNLENGLEPAE THSMVRHKDGGYSEEEDVKTCARDS GYDSLSNRLSILDRLLHTHPIWLQL SLSEEEAAEVLQAQPPGIFLVHKST KMQKKVLSLRLPCEFGAPLKEFAIK ESTYTFSLEGSGISFADLFRLIAFY CISRDVLPFTLKLPYAISTAKSEAQ LEELAQMGLNFWSSPADSKPPNLPP PHRPLSSDGVCPASLRQLCLINGVH SIKTRTPSELECSQTNGALCFINPL FLKVHSQDLSGGLKRPSTRTPNANG TERTRSPPPRPPPPAINSLHTSPRL ARTETQTSMPETVNHNKHGNVALPG TKPTPIPPPRLKKQASFLEAEGGAK TLSGGRPGAGPELELGTAGSPGGAP PEAAPGDCTRAPPPSSESRPPCHGG RQRLSDMSISTSSSDSLEFDRSMPL FGYEADTNSSLEDYEGESDQETMAP PIKSKKKRSSSFVLPKLVKSQLQKV SGVFSSFMTPEKRMVRRIAELSRDK CTYFGCLVQDYVSFLQENKECHVSS TDMLQTIRQFMTQVKNYLSQSSELD PPIESLIPEDQIDVVLEKAMHKCIL KPLKGHVEAMLKDFHMADGSWKQLK ENLQLVRQRNPQELGVFAPTPDFVD VEKIKVKFMTMQKMYSPEKKVMLLL RVCKLIYTVMENNSGRMYGADDFLP VLTYVIAQCDMLELDTEIEYMMELL DPSLLHGEGGYYLTSAYGALSLIKN FQEEQAARLLSSETRDTLRQWHKRR TTNRTIPSVDDFQNYLRVAFQEVNS GCTGKTLLVRPYITTEDVCQICAEK FKVGDPEEYSLFLFVDETWQQLAED TYPQKIKAELHSRPQPHIFHFVYKR IKNDPYGIIFQNGEEDLTTSTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | RIN2 RAB5 interacting protein 2 [ Homo sapiens (human) ] |
Official Symbol : | RIN2 |
Synonyms : | RIN2; Ras and Rab interactor 2; RAB5 interacting protein 2; MACS; RASSF4; ras and Rab interactor 2; RAB5 interacting protein 2; RAS association (RalGDS/AF-6) domain containing protein JC265; RAS association domain family 4; RAS inhibitor JC265; RAS interaction/interference protein 2 |
Gene ID : | 54453 |
mRNA Refseq : | NM_018993 |
Protein Refseq : | NP_061866 |
MIM : | 610222 |
UniProt ID : | Q8WYP3 |
Products Types
◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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