Recombinant Human RIPK1 protein, GST-tagged

• Cat.No.: RIPK1-42H
• Product Overview: Recombinant Human RIPK1 full-length ORF (ADR83242.1, 1 a.a. - 671 a.a.) protein with GST tag at N-terminal was expressed in Wheat Germ (in vitro).

Specification

• Description: Receptor-interacting serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the RIPK1 gene. RIPK1 is known to have function in a variety
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 100.3kDa
• AA Sequence: MQPDMSLNVIKMKSSDFLESAELDS GGFGKVSLCFHRTQGLMIMKTVYKG PNCIEHNEALLEEAKMMNRLRHSRV VKLLGVIIEEGKYSLVMEYMEKGNL MHVLKAEMSTPLSVKGRIILEIIEG MCYLHGKGVIHKDLKPENILVDNDF HIKIADLGLASFKMWSKLNNEEHNE LREVDGTAKKNGGTLYYMAPEHLND VNAKPTEKSDVYSFAVVLWAIFANK EPYENAICEQQLIMCIKSGNRPDVD DITEYCPREIISLMKLCWEANPEAR PTFPGIEEKFRPFYLSQLEESVEED VKSLKKEYSNENAVVKRMQSLQLDC VAVPSSRSNSATEQPGSLHSSQGLG MGPVEESWFAPSLEHPQEENEPSLQ SKLQDEANYHLYGSRMDRQTKQQPR QNVAYNREEERRRRVSHDPFAQQRP YENFQNTEGKGTAYSSAASHGNAVH QPSGLTSQPQVLYQNNGLYSSHGFG TRPLDPGTAGPRVWYRPIPSHMPSL HNIPVPETNYLGNTPTMPFSSLPPT DESIKYTIYNSTGIQIGAYNYMEIG GTSSSLLDSTNTNFKEEPAAKYQAI FDNTTSLTDKHLDPIRENLGKHWKN CARKLGFTQSQIDEIDHDYERDGLK EKVYQMLQKWVMREGIKGATVGKLA QALHQCSRIDLLSSLIYVSQN
• Applications: Enzyme-linked Immunoabsorbent Assay, Western Blot (Recombinant protein), Antibody Production, Protein Array
• Quality Control Test: 12.5% SDS-PAGE Stained with Coomassie Blue
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: RIPK1 receptor interacting serine/threonine kinase 1 [ Homo sapiens (human) ]
• Official Symbol: RIPK1
• Synonyms: RIP; RIP1; RIP-1
• Gene ID: 8737
• mRNA Refseq: HQ258488
• Protein Refseq: ADR83242
• MIM: 603453
• UniProt ID: Q13546
• Chromosome Location: 6p25.2

Reviews

02/26/2022

The proteins accepted were of very high purity and were put into experiments with satisfactory results.

03/14/2021

Customer service was patient, prompt and accurate in answering my queries.

11/23/2020

Prompt delivery, which helped me to obtain satisfactory experimental results in a short time.

Q&As

What is the relationship between RIPK1 and necrotic apoptosis?

RIPK1 is one of the most critical intracellular signaling factors mediating necrotic apoptosis.

What is the relationship between Necrostatin-1 and RIPK1?

Necrostatin-1 blocks RIPK1 phosphorylation.

What are the effects of inhibiting RIPK1 expression?

Inhibition of RIPK1 reduces astrocyte proliferation and glial scar formation and promotes recovery of brain function.

RIPK1 is closely associated with the study of which diseases?

RIPK1 is closely related to the study of stroke, neurodegenerative diseases, autoimmune diseases and other diseases.