Recombinant Human RIPK1 protein, His&Myc-tagged

• Cat.No.: RIPK1-2307H
• Product Overview: Recombinant Human RIPK1 protein(Q13546)(1-375aa), fused to N-terminal His tag and C-terminal Myc tag, was expressed in Insect Cell.

Specification

• Source: Insect Cell
• Species: Human
• Tag: His&Myc
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
  If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 46.4 kDa
• Protein length: 1-375aa
• AA Sequence: MQPDMSLNVIKMKSSDFLESAELDS GGFGKVSLCFHRTQGLMIMKTVYKG PNCIEHNEALLEEAKMMNRLRHSRV VKLLGVIIEEGKYSLVMEYMEKGNL MHVLKAEMSTPLSVKGRIILEIIEG MCYLHGKGVIHKDLKPENILVDNDF HIKIADLGLASFKMWSKLNNEEHNE LREVDGTAKKNGGTLYYMAPEHLND VNAKPTEKSDVYSFAVVLWAIFANK EPYENAICEQQLIMCIKSGNRPDVD DITEYCPREIISLMKLCWEANPEAR PTFPGIEEKFRPFYLSQLEESVEED VKSLKKEYSNENAVVKRMQSLQLDC VAVPSSRSNSATEQPGSLHSSQGLG MGPVEESWFAPSLEHPQEENEPSLQ
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Gene Information

• Gene Name: RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 [ Homo sapiens ]
• Official Symbol: RIPK1
• Synonyms: RIPK1; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor-interacting serine/threonine-protein kinase 1; RIP; RIP-1; cell death protein RIP; receptor interacting protein; receptor-interacting protein 1; serine/threonine-protein kinase RIP; RIP1; FLJ39204
• Gene ID: 8737
• mRNA Refseq: NM_003804
• Protein Refseq: NP_003795
• MIM: 603453
• UniProt ID: Q13546

Reviews

02/26/2022

The proteins accepted were of very high purity and were put into experiments with satisfactory results.

03/14/2021

Customer service was patient, prompt and accurate in answering my queries.

11/23/2020

Prompt delivery, which helped me to obtain satisfactory experimental results in a short time.

Q&As

What is the relationship between RIPK1 and necrotic apoptosis?

RIPK1 is one of the most critical intracellular signaling factors mediating necrotic apoptosis.

What is the relationship between Necrostatin-1 and RIPK1?

Necrostatin-1 blocks RIPK1 phosphorylation.

What are the effects of inhibiting RIPK1 expression?

Inhibition of RIPK1 reduces astrocyte proliferation and glial scar formation and promotes recovery of brain function.

RIPK1 is closely associated with the study of which diseases?

RIPK1 is closely related to the study of stroke, neurodegenerative diseases, autoimmune diseases and other diseases.