Recombinant Human RIPK1 Protein, His-tagged

• Cat.No.: RIPK1-45H
• Product Overview: Recombinant Human RIPK1 Protein(Phe17~Tyr289), fused with His tag at the N-terminus, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Form: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Molecular Mass: 35kDa
• Protein Length: Phe17~Tyr289
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 [ Homo sapiens ]
• Official Symbol: RIPK1
• Synonyms: RIPK1; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor-interacting serine/threonine-protein kinase 1; RIP; RIP-1; cell death protein RIP; receptor interacting protein; receptor-interacting protein 1; serine/threonine-protein kinase RIP; RIP1; FLJ39204
• Gene ID: 8737
• mRNA Refseq: NM_003804
• Protein Refseq: NP_003795
• MIM: 603453
• UniProt ID: Q13546

Reviews

02/26/2022

The proteins accepted were of very high purity and were put into experiments with satisfactory results.

03/14/2021

Customer service was patient, prompt and accurate in answering my queries.

11/23/2020

Prompt delivery, which helped me to obtain satisfactory experimental results in a short time.

Q&As

What is the relationship between RIPK1 and necrotic apoptosis?

RIPK1 is one of the most critical intracellular signaling factors mediating necrotic apoptosis.

What is the relationship between Necrostatin-1 and RIPK1?

Necrostatin-1 blocks RIPK1 phosphorylation.

What are the effects of inhibiting RIPK1 expression?

Inhibition of RIPK1 reduces astrocyte proliferation and glial scar formation and promotes recovery of brain function.

RIPK1 is closely associated with the study of which diseases?

RIPK1 is closely related to the study of stroke, neurodegenerative diseases, autoimmune diseases and other diseases.