Recombinant Human RNF213 Protein, MYC/DDK-tagged
Cat.No. : | RNF213-675H |
Product Overview : | Recombinant Human RNF213 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
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Description : | This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 118.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | RNF213 ring finger protein 213 [ Homo sapiens ] |
Official Symbol : | RNF213 |
Synonyms : | RNF213; ring finger protein 213; C17orf27, chromosome 17 open reading frame 27 , KIAA1618 , moyamoya disease 2 , Moyamoya disease 2 , MYMY2; RING finger protein 213; KIAA1554; NET57; mysterin; ALK lymphoma oligomerization partner on chromosome 17; ALO17; MYMY2; MYSTR; C17orf27; KIAA1618; MGC9929; FLJ13051; MGC46622; DKFZp762N1115; |
Gene ID : | 57674 |
mRNA Refseq : | NM_020954 |
Protein Refseq : | NP_066005 |
MIM : | 613768 |
UniProt ID : | Q63HN8 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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