Recombinant Human RNGTT Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RNGTT-5281H
• Product Overview: RNGTT MS Standard C13 and N15-labeled recombinant protein (NP_003791) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: RNGTT (RNA Guanylyltransferase And 5'-Phosphatase) is a Protein Coding gene. Diseases associated with RNGTT include Cecum Carcinoma and Cecum Adenocarcinoma. Among its related pathways are HIV Transcription Elongation and Gene Expression. Gene Ontology (GO) annotations related to this gene include GTP binding and protein tyrosine phosphatase activity. An important paralog of this gene is DUSP11.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 68.4 kDa
• AA Sequence: MAHNKIPPRWLNCPRRGQPVAGRFL PLKTMLGPRYDSQVAEENRFHPSML SNYLKSLKVKMGLLVDLTNTSRFYD RNDIEKEGIKYIKLQCKGHGECPTT ENTETFIRLCERFNERNPPELIGVH CTHGFNRTGFLICAFLVEKMDWSIE AAVATFAQARPPGIYKGDYLKELFR RYGDIEEAPPPPLLPDWCFEDDEDE DEDEDGKKESEPGSSASFGKRRKER LKLGAIFLEGVTVKGVTQVTTQPKL GEVQQKCHQFCGWEGSGFPGAQPVS MDKQNIKLLDLKPYKVSWKADGTRY MMLIDGTNEVFMIDRDNSVFHVSNL EFPFRKDLRMHLSNTLLDGEMIIDR VNGQAVPRYLIYDIIKFNSQPVGDC DFNVRLQCIEREIISPRHEKMKTGL IDKTQEPFSVRNKPFFDICTSRKLL EGNFAKEVSHEMDGLIFQPTGKYKP GRCDDILKWKPPSLNSVDFRLKITR MGGEGLLPQNVGLLYVGGYERPFAQ IKVTKELKQYDNKIIECKFENNSWV FMRQRTDKSFPNAYNTAMAVCNSIS NPVTKEMLFEFIDRCTAASQGQKRK HHLDPDTELMPPPPPKRPHPLTTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RNGTT RNA guanylyltransferase and 5-phosphatase [ Homo sapiens (human) ]
• Official Symbol: RNGTT
• Synonyms: RNGTT; RNA guanylyltransferase and 5-phosphatase; mRNA-capping enzyme; hCAP; HCE; HCE1; HCAP1; CAP1A; DKFZp686J2031
• Gene ID: 8732
• mRNA Refseq: NM_003800
• Protein Refseq: NP_003791
• MIM: 603512
• UniProt ID: O60942

Reviews

04/04/2023

Its exceptional characteristics, coupled with the manufacturer's commitment to customer satisfaction, ensure that I can pursue my scientific investigations with confidence and success.

07/09/2022

This level of support becomes invaluable, allowing researchers to focus on their scientific objectives while receiving expert guidance alongside.

08/07/2020

Its consistent performance and reproducibility have been praised by scientists who have employed it in their studies, with many reporting outstanding results and a high level of satisfaction.

Q&As

Can RNGTT protein-based therapies be used in personalized medicine?

There is potential for RNGTT protein-based therapies to be tailored to individual patients based on their specific disease characteristics.

How can RNGTT protein be targeted for clinical therapy?

Targeting RNGTT protein may offer potential therapeutic strategies for autoimmune diseases and cancer.

Can RNGTT protein be targeted for the treatment of neurodegenerative diseases?

There is emerging research exploring the potential of targeting RNGTT protein in the context of neurodegenerative diseases.

How does RNGTT protein relate to the development of autoimmune diseases?

Dysregulation of protein glycosylation mediated by RNGTT protein has been implicated in the pathogenesis of autoimmune diseases.

What are the potential clinical implications of RNGTT protein deficiency?

RNGTT protein deficiency can lead to a range of disorders, including immune system dysregulation and developmental defects.