Recombinant Human ROS1 protein, His & T7-tagged

• Cat.No.: ROS1-1185H
• Product Overview: Recombinant Human ROS1 aa. (Leu1945~Phe2222 (Accession # P08922) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 35.5kDa.
• Protein length: Leu1945~Phe2222 (Accession # P08922)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >90%
• Characteristic: The isoelectric point is 6.2.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: ROS1 ROS proto-oncogene 1, receptor tyrosine kinase [ Homo sapiens (human) ]
• Official Symbol: ROS1
• Synonyms: ROS1; ROS proto-oncogene 1, receptor tyrosine kinase; ROS; MCF3; c-ros-1; proto-oncogene tyrosine-protein kinase ROS; ROS proto-oncogene 1 , receptor tyrosine kinase; c-ros oncogene 1 , receptor tyrosine kinase; proto-oncogene c-Ros-1; transmembrane tyrosine-specific protein kinase; v-ros avian UR2 sarcoma virus oncogene homolog 1
• Gene ID: 6098
• mRNA Refseq: NM_002944.2
• Protein Refseq: NP_002935.2
• UniProt ID: P08922