Recombinant Human RPA2, T7-tagged
Cat.No. : | RPA2-2983H |
Product Overview : | Recombinant Human RPA2 (1-270 aa) is expressed inE.Coliwith a T7 tag at N-terminus. |
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Cat. No. : | RPA2-2983H |
Source : | E.Coli. |
MW : | 29247 Da. |
Purity : | 95%. |
Formulation : | 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. |
Application : | MS. SDS. |
Gene Name : | RPA2 replication protein A2, 32kDa [ Homo sapiens ] |
Synonyms : | RPA2; replication protein A2, 32kDa;OTTHUMP00000004010; RF-A protein 2; RP-A p32; RP-A p34; replication factor A protein 2; replication protein A 32 kDa subunit; replication protein A 34 kDa subunit; REPA2; RPA32; RPA2 |
Gene ID : | 6118 |
mRNA Refseq : | NM_002946 |
Protein Refseq : | NP_002937 |
MIM : | 179836 |
UniProt ID : | P15927 |
Chromosome Location : | 1p35 |
Pathway : | DNA replication; Mismatch repair; Nucleotide excision repair; Cell Cycle, Mitotic; Chromosome Maintenance; DNA Replication |
Function : | ATP binding; DNA clamp loader activity; nucleoside-triphosphatase activity; protein binding |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionTargeting RPA2 with specific inhibitors could disrupt DNA repair mechanisms in cancer cells, rendering them more susceptible to treatments like chemotherapy or radiation therapy.
RPA2 participates in the protection and maintenance of telomeres, the protective caps at the end of chromosomes, thereby contributing to cellular longevity and genomic stability.
Targeting RPA2 in therapy may pose challenges, as its essential role in normal cellular processes raises concerns about potential side effects. Careful modulation is crucial.
Yes, exploring RPA2 as a therapeutic target extends to conditions where genomic stability is compromised, such as certain genetic disorders and autoimmune diseases.
Information about specific clinical trials should be checked, but the potential use of RPA2 as a target for cancer therapy is an area of active research.
Customer Reviews (3)
Write a reviewThis commitment ensures that I have access to the most advanced and reliable protein available, enhancing the integrity and impact of my experiments.
The RPA2 protein exhibits exceptional quality, making it an ideal choice to meet my experimental requirements.
the manufacturer's customer-centric approach highlights their focus on ensuring my satisfaction.
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