Recombinant Human RRAS Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RRAS-3690H
• Product Overview: RRAS MS Standard C13 and N15-labeled recombinant protein (NP_006261) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 23.5 kDa
• AA Sequence: MSSGAASGTGRGRPRGGGPGPGDPP PSETHKLVVVGGGGVGKSALTIQFI QSYFVSDYDPTIEDSYTKICSVDGI PARLDILDTAGQEEFGAMREQYMRA GHGFLLVFAINDRQSFNEVGKLFTQ ILRVKDRDDFPVVLVGNKADLESQR QVPRSEASAFGASHHVAYFEASAKL RLNVDEAFEQLVRAVRKYQEQELPP SPPSAPRKKGGGCPCVLLTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RRAS RAS related [ Homo sapiens (human) ]
• Official Symbol: RRAS
• Synonyms: RRAS; related RAS viral (r-ras) oncogene homolog; ras-related protein R-Ras; Oncogene RRAS; p23
• Gene ID: 6237
• mRNA Refseq: NM_006270
• Protein Refseq: NP_006261
• MIM: 165090
• UniProt ID: P10301

Reviews

08/30/2021

Precise protein quantification, fundamental for data accuracy in our experiments.

01/07/2019

Dependable peptide synthesis, accelerates our peptide-focused projects effectively.

01/06/2019

Timely antibody validation, a valuable asset for our laboratory.

Q&As

How do alterations in RRAS expression or activity affect tumorigenesis and cancer therapy response?

Variations in RRAS can influence cancer development and affect how cancer cells respond to therapies.

What is the impact of RRAS on angiogenesis and vascular remodeling?

RRAS affects angiogenesis and vascular remodeling, crucial for tissue growth and repair.

What role does RRAS play in cell adhesion and migration, particularly in cancer metastasis?

RRAS is involved in cell adhesion and migration, playing a significant role in cancer cell metastasis.

How does RRAS influence immune cell activation and the immune response?

RRAS modulates immune cell activation, impacting the overall immune response.

What are the mechanisms by which RRAS modulates cellular proliferation and differentiation?

RRAS controls cellular processes like proliferation and differentiation, essential for normal development and tissue maintenance.

How does RRAS contribute to the development and progression of cardiovascular diseases?

RRAS contributes to cardiovascular diseases by influencing cell signaling pathways in heart and blood vessel cells.

How does RRAS (Related RAS Viral (R-Ras) Oncogene Homolog) influence signal transduction pathways in cells?

RRAS regulates various signal transduction pathways, affecting cell growth, survival, and differentiation.