Recombinant Human RRBP1 protein, His & T7-tagged
Cat.No. : | RRBP1-1667H |
Product Overview : | Recombinant Human RRBP1 aa. (Arg822~Val977 (Accession # Q9P2E9)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
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Description : | This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. |
Source : | E. coli |
Species : | Human |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | 30kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Arg822~Val977 (Accession # Q9P2E9) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative. |
Reconstitution : | Reconstitute in sterile ddH2O. |
Isoelectric Point : | 4.7 |
Gene Name : | RRBP1 ribosome binding protein 1 [ Homo sapiens (human) ] |
Official Symbol : | RRBP1 |
Synonyms : | RRBP1; ribosome binding protein 1; RRp; hES; ES130; ES/130; ribosome-binding protein 1; 180 kDa ribosome receptor homolog; ES/130-related protein; ribosome binding protein 1 homolog 180kDa (dog); ribosome receptor protein |
Gene ID : | 6238 |
mRNA Refseq : | NM_001042576.1 |
Protein Refseq : | NP_001036041.1 |
UniProt ID : | Q9P2E9 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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