Recombinant Human RRM2 Protein (Met1-Phe389), C-His tagged

• Cat.No.: RRM2-6206H
• Product Overview: Recombinant human RRM2 (Met1-Phe389) fused with the C-terminal His tag was expressed in mammalian cells.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: C-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 42.79 kDa
• Protein Length: Met1-Phe389
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: RRM2 ribonucleotide reductase M2 [ Homo sapiens (human) ]
• Official Symbol: RRM2
• Synonyms: RRM2; ribonucleotide reductase M2; ribonucleotide reductase M2 polypeptide; ribonucleoside-diphosphate reductase subunit M2; ribonucleotide reductase small chain; ribonucleotide reductase small subunit; R2; RR2; RR2M
• Gene ID: 6241
• mRNA Refseq: NM_001034
• Protein Refseq: NP_001025
• MIM: 180390
• UniProt ID: P31350

Reviews

05/14/2022

The professional gave me a detailed description of the RRM2 protein so that I could understand its biochemical properties.

03/31/2021

Smooth communication and timely shipment, allowing my experiment to be implemented as soon as possible.

11/20/2020

Cheap price, high quality products, worth buying again!

Q&As

What diseases has RRM2 been associated with the study of?

RRM2 has been associated with studies of liver, lung, and breast cancers.

How is RRM2 related to tumor development?

Elevated expression of RRM2 in some malignant tumors promotes tumor cell proliferation and immune escape, leading to malignant tumor progression.

What is the function of RRM2?

RRM2, which catalyzes the formation of deoxyribonucleotides from ribonucleotides, is involved in processes such as DNA repair and the cell cycle.

What is the relationship between RRM2 and ANXA1?

RRM2 interacts with ANXA1.

What is the relationship between RRM2 and RRM2B?

Both RRM2 and RRM2B are two small subunits of RR.