Recombinant Human RRM2, T7 -tagged
Cat.No. : | RRM2-30111TH |
Product Overview : | Recombinant full length protein (Human). T7 tag at N-terminus. |
- Specification
- Gene Information
- Related Products
- Download
Description : | This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. |
Conjugation : | T7 |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, 10mM DTT, pH 8 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the ribonucleoside diphosphate reductase small chain family. |
Gene Name : | RRM2 ribonucleotide reductase M2 [ Homo sapiens ] |
Official Symbol : | RRM2 |
Synonyms : | RRM2; ribonucleotide reductase M2; ribonucleotide reductase M2 polypeptide; ribonucleoside-diphosphate reductase subunit M2; |
Gene ID : | 6241 |
mRNA Refseq : | NM_001034 |
Protein Refseq : | NP_001025 |
MIM : | 180390 |
Uniprot ID : | P31350 |
Chromosome Location : | 2p25-p24 |
Pathway : | Cell Cycle, Mitotic, organism-specific biosystem; E2F mediated regulation of DNA replication, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; Fluoropyrimidine Activity, organism-specific biosystem; G1/S Transition, organism-specific biosystem; |
Function : | oxidoreductase activity; ribonucleoside-diphosphate reductase activity; ribonucleoside-diphosphate reductase activity; transition metal ion binding; |
Products Types
◆ Recombinant Protein | ||
RRM2-1960H | Recombinant Human RRM2 Protein, MYC/DDK-tagged | +Inquiry |
RRM2-1922H | Recombinant Human RRM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rrm2-5627M | Recombinant Mouse Rrm2 Protein, Myc/DDK-tagged | +Inquiry |
RRM2-632C | Recombinant Cynomolgus Monkey RRM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
RRM2-4840R | Recombinant Rat RRM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
RRM2-1545HCL | Recombinant Human RRM2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionRRM2 has been associated with studies of liver, lung, and breast cancers.
Elevated expression of RRM2 in some malignant tumors promotes tumor cell proliferation and immune escape, leading to malignant tumor progression.
RRM2, which catalyzes the formation of deoxyribonucleotides from ribonucleotides, is involved in processes such as DNA repair and the cell cycle.
RRM2 interacts with ANXA1.
Both RRM2 and RRM2B are two small subunits of RR.
Customer Reviews (3)
Write a reviewThe professional gave me a detailed description of the RRM2 protein so that I could understand its biochemical properties.
Smooth communication and timely shipment, allowing my experiment to be implemented as soon as possible.
Cheap price, high quality products, worth buying again!
Ask a Question for All RRM2 Products
Required fields are marked with *
My Review for All RRM2 Products
Required fields are marked with *
Inquiry Basket