Recombinant Human S100A10, His-tagged

• Cat.No.: S100A10-434H
• Product Overview: Recombinant human S100A10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis.
• Source: E.coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol,0.1M NaCl, 0.1mM PMSF
• Molecular Mass: 13.3 kDa (117aa) confirmed by MALDI-TOF
• Protein length: 1-97aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MPSQMEHAME TMMFTFHKFA GDKGYLTKED LRVLMEKEFP GFLENQKDPL AVDKIMKDLD QCRDGKVGFQSFFSLIAGLT IACNDYFVVH MKQKGKK
• Purity: > 90% by SDS - PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: S100A10 S100 calcium binding protein A10 [ Homo sapiens (human) ]
• Official Symbol: S100A10
• Synonyms: S100A10; S100 calcium binding protein A10; 42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG; MGC111133; OTTHUMP00000015270; annexin II ligand, calpactin I, light polypeptide; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 alcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); Protein S100-A10; S100 calcium-binding protein A10; Calpactin-1 light chain; Calpactin I light chain; p10 protein; Cellular ligand of annexin II; OTTHUMP00000015269; p11
• Gene ID: 6281
• mRNA Refseq: NM_002966
• Protein Refseq: NP_002957
• MIM: 114085
• UniProt ID: P60903
• Chromosome Location: 1q21
• Pathway: Dissolution of Fibrin Clot; Orphan transporters; Transmembrane transport of small molecules
• Function: calcium ion binding; ion channel binding; protein homodimerization activity